SNPs | Genotype/allele | HPR (n = 233) | Non-HPR (n = 441) | p | OR (95 % CI) |
---|---|---|---|---|---|
rs2251692 | AA, no. (%) | 100 (42.9) | 193 (43.8) | 0.24 | Â |
AG, no. (%) | 114 (48.9) | 195 (44.2) | Â | Â | |
GG, no. (%) | 19 (8.2) | 53 (12.0) | Â | Â | |
A allele | 314 (67.4) | 581 (65.9) | 0.58 | 0.96 (0.82–1.12) | |
G allele | 152 (32.6) | 301 (34.1) | Â | Â | |
rs13431554 | AA, no. (%) | 126 (54.1) | 289 (65.5) | <0.001 | Â |
AG, no. (%) | 85 (36.5) | 140 (31.7) | Â | Â | |
GG, no. (%) | 22 (9.4) | 12 (2.7) | Â | Â | |
A allele | 337 (72.3) | 718 (81.4) | <0.001 | 1.49 (1.22–1.82) | |
G allele | 129 (27.7) | 164 (18.6) | Â | Â | |
rs10205923 | AA, no. (%) | 28 (12.0) | 39 (8.8) | 0.24 | Â |
AG, no. (%) | 101 (43.2) | 178 (40.4) | Â | Â | |
GG, no. (%) | 105 (44.9) | 224 (50.8) | Â | Â | |
A allele | 157 (33.5) | 256 (29.0) | 0.09 | 1.16 (0.98–1.36) | |
G allele | 311 (66.5) | 626 (71.0) | Â | Â | |
rs1078533 | AA no. (%) | 5 (2.1) | 9 (2.0) | 0.68 | Â |
AC no. (%) | 40 (17.2) | 88 (20.0) | Â | Â | |
CC no. (%) | 188 (80.7) | 344 (78.0) | Â | Â | |
A allele | 50 (10.7) | 106 (12.0) | 0.48 | 0.88 (0.62–1.26) | |
C allele | 416 (89.3) | 776 (88.0) | Â | Â | |
rs2288586 | CC, no. (%) | 134 (57.5) | 283 (64.2) | 0.24 | Â |
CG, no. (%) | 87 (37.3) | 139 (31.5) | Â | Â | |
GG, no. (%) | 12 (5.2) | 19 (4.3) | Â | Â | |
C allele | 355 (76.2) | 705 (79.9) | 0.11 | 1.19 (0.96–1.46) | |
G allele | 111 (23.8) | 177 (20.1) | Â | Â | |
rs1801278 | AA no. (%) | 0 (0) | 0 (0) | 0.58 | Â |
AG no. (%) | 8 (3.4) | 19 (4.3) | Â | Â | |
GG no. (%) | 225 (96.6) | 422 (95.7) | Â | Â | |
A allele | 8 (1.7) | 19 (2.2) | 0.59 | 0.80 (0.35–1.81) | |
G allele | 458 (98.3) | 863 (97.8) | Â | Â | |
rs1896832 | AA, no. (%) | 165 (70.8) | 284 (64.4) | 0.20 | Â |
AG, no. (%) | 62 (26.6) | 147 (33.3) | Â | Â | |
GG, no. (%) | 6 (2.6) | 10 (2.3) | Â | Â | |
A allele | 392 (84.1) | 715 (81.1) | 0.16 | 0.84 (0.65–1.08) | |
T allele | 74 (15.9) | 167 (18.9) | Â | Â | |
rs956115 | CC, no. (%) | 2 (0.9) | 10 (2.3) | 0.28 | Â |
CG, no. (%) | 50 (21.5) | 107 (24.3) | Â | Â | |
GG, no. (%) | 181 (77.7) | 324 (73.5) | Â | Â | |
C allele | 54 (11.6) | 137 (14.4) | 0.15 | 1.03 (0.99–1.08) | |
G allele | 412 (88.4) | 755 (85.6) | Â | Â |