Table 2 Demographic and other baseline characteristics of patients included in the cardiovascular meta-analysis—all randomized patients (ITT population)

Mean age (years)

56.0

56.2

56.1

0.78

Age group [n (%)]

–

–

–

0.30

 <65 years

1724 (81.1)

3177 (81.8)

4901 (81.6)

 ≥65 years

401 (18.9)

708 (18.2)

1109 (18.5)

Sex [n (%)]

–

–

–

0.27

 Female

1016 (47.8)

1916 (49.3)

2932 (48.8)

 Male

1109 (52.2)

1969 (50.7)

3078 (51.2)

Ethnicity [n (%)]

–

–

–

0.23

 Hispanic or Latino

660 (31.1)

1209 (31.1)

1869 (31.1)

 Not Hispanic or Latino

1463 (68.9)

2676 (68.9)

4139 (68.9)

Race^b [n (%)]

–

–

–

0.27

 American Indian or Alaska Native

135 (6.4)

231 (6.0)

366 (6.1)

–

 Asian

271 (12.8)

509 (13.1)

780 (13.0)

–

 Black or African American

113 (5.3)

245 (6.3)

358 (6.0)

–

 White

1446 (68.1)

2656 (68.4)

4102 (68.3)

–

Mean duration of diabetes (years)

8.0

7.9

7.9

0.22

Duration of diabetes

–

–

–

0.01

 <5 years

765 (36.0)

1494 (38.5)

2259 (37.6)

 ≥5 and <10 years

659 (31.0)

1088 (28.0)

1747 (29.1)

 ≥10 years

701 (33.0)

1303 (33.5)

2004 (33.3)

Mean BMI (kg/m²)

32.4

32.3

32.3

0.51

Fasting plasma glucose

 Mean (mmol/L)

9.07

9.01

9.04

0.69

 <5.6 mmol/L [n (%)]

109 (5.2)

200 (5.2)

309 (5.2)

0.79

 ≥5.6 mmol/L [n (%)]

1994 (94.8)

3630 (94.8)

5624 (94.8)

HbA1c

 Mean (%)

8.1

8.1

8.1

0.87

 Mean (mmol/mol)

65.0

65.0

65.0

 <8 % (<63.9 mmol/mol) [n (%)]

1113 (52.6)

2039 (52.6)

3152 (52.6)

0.62

 ≥8 % (≥63.9 mmol/mol) [n (%)]

1005 (47.5)

1838 (47.4)

2843 (47.4)