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Table 2 Univariate and multivariable adjustment of HOMA-IR as predictor of clinical outcome

From: Insulin resistance, endothelial function, angiogenic factors and clinical outcome in non-diabetic patients with chest pain without myocardial perfusion defects

 

Univariate model

Multivariable model

HR (95 % CI)

p value

HR (95 % CI)

p value

Age

1.05 (1.03–1.08)

<0.001

1.04 (1.01–1.07)

0.007

Known CAD

3.27 (2.10–5.10)

<0.001

1.87 (1.15–3.05)

0.012

Gender

3.10 (1.92–5.01)

<0.001

1.92 (1.11–3.35)

0.020

HOMA-IR above median

2.72 (1.70–4.46)

<0.001

1.88 (1.09–3.26)

0.023

HDL

0.38 (0.19–0.75)

0.005

0.82 (0.41–1.63)

0.570

 Systolic blood pressure

1.01 (1.00–1.02)

0.036

1.00 (0.99–1.01)

0.693

Body mass index

1.05 (0.99–1.12)

0.120

1.00 (0.92–1.08)

0.915

  1. Survival analyses on the whole study population of non-diabetic patients with suspected myocardial ischemia. Data are presented with hazard ratio and 95 % CI, (n = 365)
  2. CI confidence interval, HDL high density lipoprotein cholesterol, HR hazard ratio Known CAD previously known coronary artery disease