From: Early changes in cardiovascular structure and function in adolescents with type 1 diabetes
 | Type 1 diabetes n = 199 | All controls n = 178 | p value |
---|---|---|---|
Sex (male:female) | 98:101 | 84:94 | 0.69 |
Age (years) | 14.4 ± 1.6 | 14.4 ± 2.1 | 0.80 |
Height (cm) | 163 ± 10 | 162 ± 11 | 0.25 |
Weight (kg) | 60.7 ± 14.3 | 54.7 ± 13.8 | <0.0001 |
BSA (m2) | 1.65 ± 0.22 | 1.57 ± 0.23 | 0.0006 |
Insulin administration (%) | |||
 Pump | 60.8 | – |  |
 Multiple injections | 30.2 | – |  |
Smoking status n (%) | |||
 Never smoked | 181 (92.8) | 63 (100) |  |
 Smoked few puffs to a whole cigarette in my life | 9 (4.6) | 0 |  |
 Only 2 to 3 cigarettes in my life | 1 (0.5) | 0 |  |
 More than 3, but fewer than 100 cigarettes in my life | 1 (0.5) | 0 |  |
 >100 cigarettes in my life, none in the past month | 1 (0.5) | 0 |  |
 >100 cigarettes in my life, some in the last month but not every day | 1 (0.5) | 0 |  |
 >100 cigarettes in my life, at least 1 cigarette every day during the last month | 2 [1] | 0 |  |
BMI (kg/m2) | 22.6 ± 4.3 | 20.6 ± 3.7 | <0.0001 |
SBP (mmHg) | 113 ± 10 | 110 ± 9 | 0.0005 |
SBP z-score for height | 0.2 ± 0.9 | −0.1 ± 0.9 | 0.0011 |
DBP (mmHg) | 62 ± 7 | 58 ± 7 | <0.0001 |
DBP z-score for height | −0.3 ± 0.6 | −0.6 ± 0.7 | <0.0001 |
MBP (mmHg) | 77 ± 7 | 75 ± 7 | 0.0053 |
PP (mmHg) | 51 ± 9 | 52 ± 8 | 0.48 |
HR (bpm) | 66 ± 9 | 68 ± 12 | 0.036 |
Diabetes duration (years) | 7.2 ± 3.1 | – | − |
Glucose (mmol/l) | 9.7 ± 4.4 | 4.7 ± 0.7 | <0.0001 |
HbA1c (%) | 0.085 ± 0.012 | 0.054 ± 0.002 | <0.0001 |
HbA1c mmol/mol | 84.9 ± 12.4 | 53.8 ± 2.4 | <0.0001 |
Cholesterol (mmol/L) | 4.3 ± 0.88 | 4.24 ± 0.83 | 0.5158 |
HDL cholesterol (mmol/L) | 1.6 ± 0.36 | 1.46 ± 0.28 | 0.0004 |
LDL cholesterol (mmol/L) | 2.3 ± 0.71 | 2.36 ± 0.74 | 0.6109 |
Triglycerides (mmol/L) | 0.84 ± 0.37 | 0.93 ± 0.40 | 0.0945 |
Creatinine (mmol/L) | 54 ± 9 | 56 ± 11 | 0.1149 |
eGFR (mL/min/1.73 m2) | 113 ± 17 | 108 ± 17 | 0.0405 |