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Table 1 Clinical measurements of adolescents with type 1 diabetes versus all controls

From: Early changes in cardiovascular structure and function in adolescents with type 1 diabetes

 

Type 1 diabetes n = 199

All controls n = 178

p value

Sex (male:female)

98:101

84:94

0.69

Age (years)

14.4 ± 1.6

14.4 ± 2.1

0.80

Height (cm)

163 ± 10

162 ± 11

0.25

Weight (kg)

60.7 ± 14.3

54.7 ± 13.8

<0.0001

BSA (m2)

1.65 ± 0.22

1.57 ± 0.23

0.0006

Insulin administration (%)

 Pump

60.8

–

 

 Multiple injections

30.2

–

 

Smoking status n (%)

 Never smoked

181 (92.8)

63 (100)

 

 Smoked few puffs to a whole cigarette in my life

9 (4.6)

0

 

 Only 2 to 3 cigarettes in my life

1 (0.5)

0

 

 More than 3, but fewer than 100 cigarettes in my life

1 (0.5)

0

 

 >100 cigarettes in my life, none in the past month

1 (0.5)

0

 

 >100 cigarettes in my life, some in the last month but not every day

1 (0.5)

0

 

 >100 cigarettes in my life, at least 1 cigarette every day during the last month

2 [1]

0

 

BMI (kg/m2)

22.6 ± 4.3

20.6 ± 3.7

<0.0001

SBP (mmHg)

113 ± 10

110 ± 9

0.0005

SBP z-score for height

0.2 ± 0.9

−0.1 ± 0.9

0.0011

DBP (mmHg)

62 ± 7

58 ± 7

<0.0001

DBP z-score for height

−0.3 ± 0.6

−0.6 ± 0.7

<0.0001

MBP (mmHg)

77 ± 7

75 ± 7

0.0053

PP (mmHg)

51 ± 9

52 ± 8

0.48

HR (bpm)

66 ± 9

68 ± 12

0.036

Diabetes duration (years)

7.2 ± 3.1

–

−

Glucose (mmol/l)

9.7 ± 4.4

4.7 ± 0.7

<0.0001

HbA1c (%)

0.085 ± 0.012

0.054 ± 0.002

<0.0001

HbA1c mmol/mol

84.9 ± 12.4

53.8 ± 2.4

<0.0001

Cholesterol (mmol/L)

4.3 ± 0.88

4.24 ± 0.83

0.5158

HDL cholesterol (mmol/L)

1.6 ± 0.36

1.46 ± 0.28

0.0004

LDL cholesterol (mmol/L)

2.3 ± 0.71

2.36 ± 0.74

0.6109

Triglycerides (mmol/L)

0.84 ± 0.37

0.93 ± 0.40

0.0945

Creatinine (mmol/L)

54 ± 9

56 ± 11

0.1149

eGFR (mL/min/1.73 m2)

113 ± 17

108 ± 17

0.0405

  1. Blood work, smoking status data were available for a subgroup of n = 63 controls
  2. Data are mean ± SD. BSA body surface area, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, PP pulse pressure, HR heart rate, PP pulse pressure, HR heart rate, HbA1c haemoglobin A1c, HDL high-density lipoprotein, LDL low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate