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Fig. 8 | Cardiovascular Diabetology

Fig. 8

From: Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes

Fig. 8

Concentration-response curves of endothelium-deprived aortic rings from control and STZ-diabetic rats precontracted with 0.1 µM noradrenaline and incubated with increasing concentrations of adenosine in the presence or absence of the NO synthase inhibitor L-NMA (10 µM). n = 5–7. Diabetes + NMA vs. diabetes, P < 0.001 (two-way ANOVA). Control vs. diabetes and control + NMA vs. control, ns not significant

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Cardiovascular Diabetology

ISSN: 1475-2840