Skip to main content
Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer 18F-fluoromethylcholine

Fig. 6

Comparison of 18F-FMCH and 18F-FDG target-to-background ratios in non-diabetic LDLR−/−ApoB100/100 and diabetic IGF-II/LDLR−/−ApoB100/100 atherosclerotic mice. The plaque-to-wall uptake ratio measured from autoradiography is higher with 18F-FMCH as compared with 18F-FDG in diabetic mice. The 18F-FMCH aorta-to-blood ratio measured ex vivo by gamma counting is lower as compared with 18F-FDG in non-diabetic mice. 18F-FMCH shows a significantly higher aorta-to-myocardium ratio in both mouse strains

Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840