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Table 4 Test characteristics of clinical data for prediction of coronary artery disease detected by coronary CTA

From: Use of imaging and clinical data to screen for cardiovascular disease in asymptomatic diabetics

  Definition of positive Frequency (total n = 98) (%) Sensitivity (%) Specificity (%)
Clinical variables
 Age ≥50 years Age ≥50 years 75 (77) 83.7 29.1
 Age ≥55 years Age ≥55 years 44 (44.9) 60.5 67.3
High risk clinical criteria
 Hypertension History of hypertension, current treatment, or SBP ≥ 140 mmHg 65 (66.3) 81.4 45.5
 Hyperlipidemia LDL cholesterol ≥130 mg/dL or statin therapy 65 (66.3) 76.7 41.8
 Insulin use Current insulin use at time of CTA 22 (22.5) 34.9 87.3
 Poor glycemic control Hemoglobin A1c ≥ 8.0 % 30 (30.6) 46.5 81.8
 Long duration of diabetes Duration of DM > 6 years 33 (33.7) 51.2 80.0
Combinations of high risk clinical criteria
 At least 1 high risk clinical criterion ≥1 criterion defined above 87 (88.8) 95.3 16.4
 At least 2 high risk clinical criteria ≥2 criteria defined above 65 (66.3) 86.0 49.1
 At least 3 high risk clinical criteria ≥3 criteria defined above 38 (38.8) 65.1 81.8
 At least 4 high risk clinical criteria ≥4 criteria defined above 15 (15.3) 27.9 94.5
 At least 5 high risk clinical criteria 5 criteria defined above 8 (8.2) 16.3 98.2
  1. Coronary artery disease defined as the presence of any coronary artery plaque on CTA