Table 4 Test characteristics of clinical data for prediction of coronary artery disease detected by coronary CTA
From: Use of imaging and clinical data to screen for cardiovascular disease in asymptomatic diabetics
|  | Definition of positive | Frequency (total n = 98) (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|
Clinical variables | ||||
 Age ≥50 years | Age ≥50 years | 75 (77) | 83.7 | 29.1 |
 Age ≥55 years | Age ≥55 years | 44 (44.9) | 60.5 | 67.3 |
High risk clinical criteria | ||||
 Hypertension | History of hypertension, current treatment, or SBP ≥ 140 mmHg | 65 (66.3) | 81.4 | 45.5 |
 Hyperlipidemia | LDL cholesterol ≥130 mg/dL or statin therapy | 65 (66.3) | 76.7 | 41.8 |
 Insulin use | Current insulin use at time of CTA | 22 (22.5) | 34.9 | 87.3 |
 Poor glycemic control | Hemoglobin A1c ≥ 8.0 % | 30 (30.6) | 46.5 | 81.8 |
 Long duration of diabetes | Duration of DM > 6 years | 33 (33.7) | 51.2 | 80.0 |
Combinations of high risk clinical criteria | ||||
 At least 1 high risk clinical criterion | ≥1 criterion defined above | 87 (88.8) | 95.3 | 16.4 |
 At least 2 high risk clinical criteria | ≥2 criteria defined above | 65 (66.3) | 86.0 | 49.1 |
 At least 3 high risk clinical criteria | ≥3 criteria defined above | 38 (38.8) | 65.1 | 81.8 |
 At least 4 high risk clinical criteria | ≥4 criteria defined above | 15 (15.3) | 27.9 | 94.5 |
 At least 5 high risk clinical criteria | 5 criteria defined above | 8 (8.2) | 16.3 | 98.2 |