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Table 1 Patient characteristics

From: Use of imaging and clinical data to screen for cardiovascular disease in asymptomatic diabetics

  All subjects n = 98 Coronary artery disease n = 43 (43.9 %) No coronary artery disease n = 55 (56.1 %) p Value
Demographics
 Age, years 54.5 ± 6.1 56.5 ± 5.8 53.0 ± 5.9 <0.01
 Female sex (#, %) 63 (64.3 %) 24 (55.8 %) 39 (70.9 %) 0.12
Race (#, %)
 Caucasian 64 (65.3 %) 33 (76.7 %) 31 (56.4 %) 0.03
 Black 19 (19.4 %) 4 (9.3 %) 15 (27.3 %)
 Asian 7 (7.1 %) 1 (2.3 %) 6 (10.9 %)
 Other 8 (8.2 %) 5 (11.6 %) 3 (5.5 %)
Clinical data
 Body mass index 29.4 ± 4.7 29.5 ± 4.8 29.3 ± 4.7 0.83
 Abdominal circumference, cm 103.0 ± 12.1 105.0 ± 12.0 101.4 ± 12.1 0.15
 Systolic blood pressure, mmHg 120.9 ± 17.2 125.3 ± 17.3 117.4 ± 16.5 0.02
 Diastolic blood pressure, mmHg 71.9 ± 11.9 73.9 ± 12.3 70.3 ± 11.4 0.15
 Treatment for hypertension (#, %) 64 (65.3) 34 (79.1 %) 30 (54.5 %) 0.01
 Duration of diabetes, years 5.2 ± 3.3 6.5 ± 3.2 4.2 ± 3.0 <0.01
 History of hyperlipidemia (#, %) 55 (56.1 %) 26 (60.5 %) 29 (52.7 %) 0.44
 Family history of coronary artery disease (#, %) 10 (10.2 %) 7 (16.3 %) 3 (5.5 %) 0.08
Smoking status (#, %)
 Current smoker 20 (20.4 %) 10 (23.3 %) 10 (18.2 %) 0.74
 Former smoker 8 (8.2 %) 4 (9.3 %) 4 (7.3 %)
 Never smoker 70 (71.4 %) 29 (67.4 %) 41 (74.5 %)
 Framingham risk score (10-year estimated risk) (median, interquartile range) 13.0 % (8.0–16 %) 13.0 % (10–20 %) 13.0  % (8–16 %) 0.07
 2013 AHA/ACC risk calculator (10-year risk of atherosclerotic cardiovascular disease) (median, interquartile range) 8.2 % (4.0–16.0 %) 13.5 % (5.5–19.7 %) 7.0 % (2.3–13 %) <0.01
 UKPDS risk engine 10-year predicted risk of coronary heart disease (median, interquartile range) 11.4 % (5.2–19.4 %) 17.9 % (11.7–26.2 %) 7.2 % (3.8–11.6 %) <0.01
Laboratory data
 Hemoglobin A1c 7.3 ± 1.7 % 8.0 ± 1.7 % 6.8 ± 1.5 % <0.01
 Total cholesterol, mg/dL 193.5 ± 39.7 198.5 ± 46.6 189.7 ± 33.3 0.28
 HDL cholesterol, mg/dL 45.5 ± 13.2 46.7 ± 14.3 44.5 ± 12.5 0.44
 LDL cholesterol, mg/dL 116.7 ± 35.1 120.6 ± 41.4 113.7 ± 29.2 0.33
 Triglycerides, mg/dL (median, interquartile range) 133 (103–198) 148 (101–213) 129 (103–194) 0.46
 Microalbuminuria, mg/24 h (median, interquartile range) 5.8 (3.9–11.8) 8.1 (3.9–18.7) 5.4 (3.7–9.0) 0.09
Medications     
 Insulin use (#, %) 22 (22.5 %) 15 (34.8 %) 7 (12.7 %) <0.01
 Oral hypoglycemic (#, %) 82 (83.7 %) 39 (90.7 %) 43 (78.2 %) 0.10
 ACE or ARB (#, %) 50 (51.0 %) 27 (62.8 %) 23 (41.8 %) 0.04
 Statin (#, %) 45 (45.9 %) 25 (58.1 %) 20 (26.4 %) 0.03
 Aspirin (#, %) 33 (33.7 %) 19 (44.2 %) 14 (25.5 %) 0.052
  1. Values given are mean ± standard deviation unless otherwise specified
  2. p Values were calculated using two-tailed t test and Chi squared test; Kruskal–Wallis test was used for comparison of medians