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Table 1 Clinical data of patients and Cox regression analysis in association with cardiovascular events

From: Incremental prognostic value of global longitudinal strain in patients with type 2 diabetes mellitus

Variable

Total (n = 247)

B

HR (95 % CI)

P

Demographic data

 Age, years

59.8 ± 9.5

0.07

1.08 (1.03–1.13)

<0.01

 Female, n (%)

120 (48.6)

0.77

2.15 (0.80–5.76)

0.13

 Body mass index, kg/m2

26.2 ± 4.8

−0.08

0.93 (0.82–1.04)

0.20

 SBP (mmHg)

136.3 ± 18.7

−0.001

1.00 (0.97–1.03)

0.93

 DBP (mmHg)

79.1 ± 8.8

−0.03

0.97 (0.92–1.03)

0.33

Medical history

 Diabetes durations, years

13.5 ± 8.2

0.03

1.03 (0.99–1.08)

0.15

 Hypertension, n (%)

186 (75.3)

1.06

2.90 (0.67–12.6)

0.16

 Hyperlipidemia, n (%)

130 (52.6)

1.09

2.96 (1.05–8.37)

0.04

 Smoking, n (%)

55 (22.3)

0.17

1.19 (0.39–3.64)

0.76

Medication

 ACEI/ARB, n (%)

134 (54.3)

0.39

1.48 (0.58–3.78)

0.42

 Calcium channel blocker, n (%)

105 (42.5)

0.57

1.76 (0.69–4.47)

0.23

 B-blocker, n (%)

55 (22.3)

0.10

1.11 (0.36–3.37)

0.86

 Biguanides, n (%)

210 (85.0)

−0.23

0.80 (0.28–2.30)

0.67

 Insulin (%)

110 (44.5)

1.09

2.96 (1.12–7.82)

0.03

Blood chemistry

 FBG (mmol/L)

8.0 ± 2.5

−0.26

0.77 (0.58–1.02)

0.06

 HbA1c (%)

7.8 ± 1.4

−0.30

0.74 (0.49–1.13)

0.16

 TG (mmol/L)

1.4 ± 1.0

−0.24

0.79 (0.43–1.45)

0.44

 TC (mmol/L)

4.5 ± 0.8

−0.16

0.86 (0.50–1.48)

0.58

 HDL (mmol/L)

1.3 ± 0.4

0.81

2.25 (0.79–6.37)

0.13

 LDL (mmol/L)

2.5 ± 0.7

−0.49

0.61 (0.29–1.30)

0.20

 Creatinine (mmol/L)

80.2 ± 39.2

0.01

1.01 (1.00–1.01)

<0.01

  1. Italic values indicate statistically significant with P < 0.05
  2. ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor antagonist, CI confidence interval, DBP diastolic blood pressure, FBG fasting blood glucose, HbA1c hemoglobinA1c, HDL high-density lipoprotein cholesterol, HR hazard ratio, LDL low-density lipoprotein cholesterol, SBP systolic blood pressure, TC total cholesterol, TG triglyceride