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Table 2 Baseline patients' characteristics used as confirmation cohort

From: Urinary alpha-1 antitrypsin and CD59 glycoprotein predict albuminuria development in hypertensive patients under chronic renin-angiotensin system suppression

 

N (n = 47)

dnHA (n = 20)

MHA (n = 23)

P value

Age (years)

65 ± 11

69 ± 7

65 ± 12

0.382

Sex (male), %

34

70

61

0.012

BMI (kg/m2)

31 ± 5

30 ± 4

31 ± 5

0.796

Current smoking, %

13

15

13

0.969

Total cholesterol (mg/dl)

186 ± 29

166 ± 27

170 ± 31

0.035

Triglycerides (mg/dl)

119 ± 53

130 ± 70

139 ± 74

0.488

HDL cholesterol (mg/dl)

56 ± 13

51 ± 9

44 ± 12

0.0003

LDL cholesterol (mg/dl)

106 ± 28

90 ± 19

100 ± 24

0.088

Glycaemic (mg/dl)

118 ± 42

123 ± 26

119 ± 34

0.387

Uric acid (mg/dl)

4.9 ± 1.5

6.3 ± 1.5

6.9 ± 1.7

<0.0001

Creatinine clearance rate (mg/ml)

101 ± 40

97 ± 47

76 ± 41

0.138

eGFR (ml/min/1.73 m2)

81 ± 18

68 ± 19

64 ± 29

0.024

Systolic blood pressure (mmHg)

138 ± 18

139 ± 22

140 ± 28

0.975

Diastolic blood pressure (mmHg)

81 ± 11

81 ± 11

82 ± 17

0.993

ACR (mg/g)

11 ± 13

211 ± 388

662 ± 910

<0.0001

Diabetes mellitus, %

32

60

52

0.066

  1. Values expressed as mean ± SD or percentages (%)
  2. BMI body mass index, HDL high-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, N normoalbuminuria, dnHA de novo high albuminuria, MHA maintained high albuminuria