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Table 1 Demographic, clinical and biochemical data of the study population

From: Apolipoprotein E gene polymorphism and risk of type 2 diabetes and cardiovascular disease

Variable

Controls (n = 84)

T2DM (n = 100)

T2DM + CVD (n = 100)

Age (years)

51.8 ± 5.2

50.9 ± 7.5

58.3 ± 7.2**

Sex (male/female)

45/39

57/43

74/26**†

BMI (kg/m2)

23.21 ± 4.62

27.59 ± 4.90*

29.81 ± 5.55**

SBP (mmHg)

115.3 ± 9.6

131.5 ± 19.7*

145.1 ± 22.6**†

DBP (mmHg)

77.6 ± 6.9

79.7 ± 18.0*

90.6 ± 9.7**†

Hypertension (%)

–

31.4

94.7†

Smokers (%)

11.1

7.8

15.7†

Physical activity (%)

66.7

54.9

31.6**†

Diabetes duration (years)

–

8.4 ± 7.2

13.3 ± 7.4†

Dyslipidemia (%)

–

72.5

92.1†

Glucose (mg/dL)

85 ± 9.5

147.1 ± 64.1*

161 ± 66.2**

HbA1c (%)

5.3 ± 0.6

6.4 ± 1.2*

6.6 ± 1.3**

Triglyceride (mg/dL)

118.3 ± 31.1

145.6 ± 72*

164.5 ± 66.2**

TC (mg/dL)

175.7 ± 16

192.1 ± 48.4*

212.7 ± 47.9**†

LDL-C (mg/dL)

104.7 ± 7

118.22 ± 38.9*

123 ± 43.7**

HDL-C (mg/dL)

53.9 ± 9.7

49.2 ± 11.2*

43.9 ± 11.8**†

VLDL-C (mg/dL)

17.1 ± 24.2

29.1 ± 14.4*

39.6 ± 22.9**†

Non-HDL-C (mg/dL)

121.14 ± 15.9

147.8 ± 44.9*

162.7 ± 47.7*†

TC/HDL-C

3.3 ± 0.6

4.4 ± 1.2*

4.5 ± 1.2**

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c hemoglobin A1C, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, VLDL-C very low density lipoprotein cholesterol
  2. * Significant p in comparison between controls and T2DM
  3. ** Significant p in comparison between controls and T2DM + CVD
  4. †Significant p in comparison between T2DM and T2DM + CVD