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Table 4 OR (95 % CI) by binary logistic regression models for nephropathy with ACR as dependent variable

From: Higher serum betatrophin level in type 2 diabetes subjects is associated with urinary albumin excretion and renal function

Models

Covariates

ACR (n = 141)

Normal (n = 106)

Nephropathy (n = 35)

OR (95 % CI)

P

OR (95 % CI)

P

Model 1

Betatrophin

1.00

5.63 (2.17–14.57)

<0.001*

DM duration

1.00

1.08 (1.00–1.15)

0.040*

hsCRP

1.00

1.91 (0.91–3.98)

0.086

SBP

1.00

1.03 (0.99–1.06)

0.103

HbA1c

1.00

1.11 (0.86–1.44)

0.434

TG

1.00

1.00 (0.99–1.01)

0.092

Model 2

Betatrophin

1.00

6.36 (2.78–14.55)

<0.001*

DM duration

1.00

1.09 (1.03–1.16)

0.002*

hsCRP

1.00

2.90 (1.17–7.20)

0.022*

SBP

1.00

1.03 (1.01–1.06)

0.012*

HbA1c

1.00

1.27 (1.03–1.56)

0.026*

TG

1.00

1.01 (1.00–1.01)

0.005*

Model 3

Betatrophin

1.00

5.79 (2.51–13.32)

<0.001*

DM duration

1.00

1.10 (1.05–1.17)

<0.001*

hsCRP

1.00

3.19 (1.28–7.97)

0.013*

SBP

1.00

1.04 (1.01–1.06)

0.004*

HbA1c

1.00

1.33 (1.08–1.64)

0.007*

TG

1.00

1.01 (1.00–1.01)

0.006*

Model 4

Betatrophin

1.00

5.43 (2.44–12.09)

<0.001*

DM duration

1.00

1.10 (1.04–1.16)

0.001*

hsCRP

1.00

2.44 (1.10–5.43)

0.029*

SBP

1.00

1.03 (1.01–1.06)

0.010*

HbA1c

1.00

1.28 (1.04–1.56)

0.018*

TG

1.00

1.00 (1.00–1.01)

0.014*

Model 5

Betatrophin

1.00

5.65 (2.39–13.33)

<0.001*

DM duration

1.00

1.10 (1.03–1.16)

0.002*

hsCRP

1.00

2.73 (1.11–6.72)

0.029*

SBP

1.00

1.03 (1.00–1.06)

0.021*

HbA1c

1.00

1.26 (1.01–1.56)

0.036*

TG

1.00

1.01 (1.00–1.01)

0.017*

  1. Model 1 unadjusted, Model 2 age adjusted, Model 3 sex adjusted, Model 4 BMI adjusted, Model 5 age, sex, and BMI adjusted, hsCRP high sensitive C-reactive protein, SBP systolic blood pressure, HbA1c hemoglobin A1c, TG triglycerides
  2. * P < 0.05 is significant in all model