Fig. 4
From: Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
Insulin injections increase body mass, but not heart mass in mice. 16-week-old male mice received injections of PBS (daily), insulin (INS; daily; 0.75 mg/kg), myriocin (MYR, thrice weekly; 3 mg/kg), or INS + MYR for 28 d. Body mass increased in the INS-treated mice only (a; n = 6). Heart mass was measured in all mice (b, c; n = 6). *P < 0.05 for INS vs. PBS; #P < 0.05 for INS + MYR vs. INS alone