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Table 3 Left ventricular geometry and function determined by cine MRI of control rats and rats on HFD for 6 weeks

From: Early impairment of coronary microvascular perfusion capacity in rats on a high fat diet

 

Control

HFD

Baseline (N = 9)

Adenosine (N = 9)

Baseline (N = 9)

Adenosine (N = 9)

Heart rate (bpm)

341 ± 13

312 ± 26*

386 ± 7

320 ± 16*

EDV (µl)

320 ± 15

380 ± 23*

295 ± 21

353 ± 36*

ESV (µl)

104 ± 12

108 ± 22

79 ± 11

79 ± 14

SV (µl)

216 ± 14

271 ± 34*

216 ± 20

274 ± 36*

EF (%)

67 ± 3

70 ± 7

73 ± 4

76 ± 4

Wall thickness (mm)

 LV free wall

1.49 ± 0.29

 

1.64 ± 0.24

 

 Septum

1.58 ± 0.22

 

1.67 ± 0.21

 
  1. Data are expressed as mean ± SEM
  2. HFD high fat diet, EDV end-diastolic volume, ESV end-systolic volume, SV stroke volume, EF ejection fraction
  3. * p < 0.05 adenosine effect
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Cardiovascular Diabetology

ISSN: 1475-2840