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Table 2 The comparisons of clinical variables according to the tertile of omentin levels

From: Association of serum omentin levels with cardiac autonomic neuropathy in patients with type 2 diabetes mellitus: a hospital-based study

 

1st tertile

2nd tertile

3rd tertile

P value (P for trend)

Omentin (ng/mL)

353 ± 36

459 ± 35

770 ± 418

<0.001

Age

54.8 ± 6.0

55.8 ± 8.3

62.1 ± 8.3

<0.001

Men/women

20/12

19/13

17/16

0.652

Duration of DM (years)

9.1 ± 5.7

9.9 ± 6.8

8.4 ± 5.5

0.779

Body mass index (kg/m2)

24.8 ± 2.7

25.6 ± 2.5

24.1 ± 2.8

0.071

WC (cm)

83.6 ± 8.6

88.1 ± 9.1

87.4 ± 8.0

0.160

Hypertension (%)

20/12(37.5)

19/13(40.6)

18/14(43.8)

0.878

Systolic BP (mmHg)

120.0 ± 13.9

121.9 ± 9.6

126.2 ± 17.6

0.209

Diastolic BP (mmHg)

75.3 ± 9.7

73.3 ± 7.1

76.1 ± 8.8

0.415

Current smoking, n (%)

7 (21.9)

7 (22.6)

5 (16.1)

0.785

Alcohol intake, n (%)

12 (37.5)

9 (29)

9 (29)

0.706

HbA1C (mmol/mol) (%)

53 (7)

56 (7.3)

54 (7.1)

0.652

FPG (mmol/L)

6.9 ± 1.1

8.0 ± 2.3

7.2 ± 2.2

0.070

Total cholesterol (mmol/L)

3.8 ± 0.5

4.2 ± 1.1

3.4 ± 1.0

0.051

LDL-cholesterol (mmol/L)

2.2 ± 0.4

2.5 ± 0.7

2.3 ± 0.7

0.120

HDL-cholesterol (mmol/L)

1.2 ± 0.3

1.3 ± 0.3

1.3 ± 0.3

0.144

Triglycerides (mmol/L)

1.3 (0.8–1.3)

1.3 (0.8–2.0)

1.2 (1.0–1.8)

0.786

hsCRP

0.07 (0.04–0.12)

0.09 (0.06–0.13)

0.07 (0.06–0.13)

0.359

Creatinine (μmol/L)

80 ± 9

124 ± 194

88 ± 27

0.648

Urinary albumin (mg/g)

9.2 ± 9.0

17.7 ± 27.9

21.8 ± 37.4

0.561

Insulin (fasting) (uIU/mL)

9.5 ± 4.8

9.9 ± 5.9

8.3 ± 3.7

0.558

c-peptide (fasting) (ng/mL)

2.3 ± 1.2

2.3 ± 1.2

2.1 ± 0.9

0.705

HOMA-IR

2.89 ± 1.45

3.45 ± 2.04

2.61 ± 1.26

0.293

ABI

1.13 ± 0.17

1.14 ± 0.05

1.14 ± 0.07

0.222

PWV (cm/s)

1381 ± 194

1490 ± 202

1605 ± 265

0.002 (p < 0.001)

CAN points

1.1 ± 0.8

1.3 ± 0.8

1.9 ± 1.3

0.013 (p = 0.003)

DPN, n (%)

13 (41.9) 

15 (50) 

10 (34.5)

0.483

CAN, n (%)

6 (20.7)

11 (39.3)

13 (52)

0.05 (p = 0.017)

DN, n (%)

1 (3.0)

6 (20)

5(17.2)

0.118 

DR, n (%)

10 (32.3)

10 (34.5)

7 (23.3)

0.610 

ACEI/ARB

7 (21.9)

13 (40.6)

12 (36.4)

0.246

Statin

17 (53.1)

21 (65.6)

22 (66.7)

0.461

  1. Data are shown as mean ± SD, median (interquartile range) or as n (%)
  2. DM diabetes mellitus, WC waist circumference, BP blood pressure, HbA1 C hemoglobin A1C, FPG fasting plasma glucose, LDL low density lipoprotein, HDL high density lipoprotein, hsCRP high-sensitivity C-reactive protein, HOMA-IR homeostasis model assessment-insulin resistance, ABI ankle-brachial index, PWV pulse wave velocity, CAN cardiac autonomic neuropathy, DPN diabetic peripheral neuropathy, DN diabetic nephropathy, DR diabetic retinopathy, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker