Fig. 2
From: SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
Up-regulation of SIRT1 improved cardiac function after MI/R in diabetic rats. a mRNA expression of SIRT1. b Protein expression of SIRT1. c SIRT1 activity. d LVDP, left ventricular developed pressure. e, f ±LV dP/dtmax, the instantaneous first derivation of left ventricle pressure. NS, non-diabetic sham rats; NIR, non-diabetic I/R rats receiving Ad-GFP; DS diabetic sham rats; DIR diabetic I/R rats receiving Ad-GFP; Ad.SIRT1, diabetic I/R rats receiving Ad-SIRT1. Values are mean ± SEM. n = 8. *P < 0.05, **P < 0.01 vs. NS; # P < 0.05, ## P < 0.01 vs. NIR; τ P < 0.05, ττ P < 0.01 vs. DIR