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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Corin is down-regulated and exerts cardioprotective action via activating pro-atrial natriuretic peptide pathway in diabetic cardiomyopathy

Fig. 5

The effect of corin deficiency on H9c2 cardiomyoblasts proliferation. a, b The silencing efficiency of Corin-siRNA sequence 1 and sequence 2 in H9c2 cardiomyoblasts was measured by real-time qPCR (n = 6 in each group) and western blot, compared with negative control-siRNA (NC-siRNA) group. c Morphological alterations of H9c2 cardiomyoblasts proliferation after transfection 0 and 48 h. Bar 100 μm. d H9c2 cardiomyoblasts were transfected 48 h later, cell proliferation was assayed by MTT (n = 5 in each group). e Viable cell count was performed using trypan blue at 48 h. Data represents 3 replicates and 3 repeats. Data are presented as mean ± SD. *P < 0.05 and **P < 0.01 versus NC-siRNA

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