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Table 4 With multiple regression analysis evolution of TOD and vascular structure and function parameters as dependent variables and average risk factors and drugs used as independent variable

From: Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD-DIABETES study

Dependent variable

β

CI 95 %

p value

IMT average mean

 Age

0.001

−0.001 to 0.002

0.651

 Sex

0.022

−0.009 to 0.052

0.158

ABI

 Age

0.003

0.001 to 0.0060

0.028

 Sex

0.048

−0.010 to 0.105

0.104

 Years of evolution of diabetes

−0.006

−0.011 to −0.001

0.017

PWV

 Age

0.044

0.007 to 0.081

0.021

 Sex

0.111

−0.958 to 0.736

0.796

 HbA1C-mean

0.501

0.102 to 0.901

0.014

eGFR

 Age

−0.222

−0.493 to −0.049

0.107

 Sex

5.557

−0.630 to 11.744

0.078

 BMI-mean

−0.813

−1.461 to −0.166

0.014

Cornell VDP

 Age

2.417

−3.990 to 8.824

0.456

 Sex

9.572

−5.091 to 24.235

0.198

  1. Dependent variable: Differences between the final and baseline assessment: (IMT intima-media thickness of common carotid artery, ABI ankle brachial index, PWV pulse wave velocity, eGFR estimated glomerular filtration rate, Cornell VDP cornell voltage duration product)
  2. Muliple linear regression by Stepwise method adjusted for: Age and gender (1 = men, 2 = women)
  3. Indepedent variable: years of evolution of diabetes. Smoker’s (1 = Yes, 0 = No). Mean values of the four measurements taken during the follow-up: (atherogenic index. Mean blood pressure. Body mass index. HbA1c; HOMA-IR mean: (Homeostasis Model Assessment Insulin Resistance). Antihypertensive drugs mean. Lipid lowering drugs mean and antidiabetic drugs mean)
  4. Italic values indicate statistical association