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Table 4 With multiple regression analysis evolution of TOD and vascular structure and function parameters as dependent variables and average risk factors and drugs used as independent variable

From: Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD-DIABETES study

Dependent variable β CI 95 % p value
IMT average mean
 Age 0.001 −0.001 to 0.002 0.651
 Sex 0.022 −0.009 to 0.052 0.158
ABI
 Age 0.003 0.001 to 0.0060 0.028
 Sex 0.048 −0.010 to 0.105 0.104
 Years of evolution of diabetes −0.006 −0.011 to −0.001 0.017
PWV
 Age 0.044 0.007 to 0.081 0.021
 Sex 0.111 −0.958 to 0.736 0.796
 HbA1C-mean 0.501 0.102 to 0.901 0.014
eGFR
 Age −0.222 −0.493 to −0.049 0.107
 Sex 5.557 −0.630 to 11.744 0.078
 BMI-mean −0.813 −1.461 to −0.166 0.014
Cornell VDP
 Age 2.417 −3.990 to 8.824 0.456
 Sex 9.572 −5.091 to 24.235 0.198
  1. Dependent variable: Differences between the final and baseline assessment: (IMT intima-media thickness of common carotid artery, ABI ankle brachial index, PWV pulse wave velocity, eGFR estimated glomerular filtration rate, Cornell VDP cornell voltage duration product)
  2. Muliple linear regression by Stepwise method adjusted for: Age and gender (1 = men, 2 = women)
  3. Indepedent variable: years of evolution of diabetes. Smoker’s (1 = Yes, 0 = No). Mean values of the four measurements taken during the follow-up: (atherogenic index. Mean blood pressure. Body mass index. HbA1c; HOMA-IR mean: (Homeostasis Model Assessment Insulin Resistance). Antihypertensive drugs mean. Lipid lowering drugs mean and antidiabetic drugs mean)
  4. Italic values indicate statistical association