Table 2 Changes in target organ damage and arterial stiffness by gender
Men | Baseline (n = 71) | 1st year (n = 69) | 2nd year (n = 69) | 3rd year (n = 69) | p |
|---|---|---|---|---|---|
Vascular | |||||
C-IMT average (mm)¶ | 0.779 ± 0.127 | 0.776 ± 0.123 | 0.769 ± 0.123 | 0.796 ± 0.126 | 0.005 |
Plaques carotid n (%) | 16 (23.2) | 15 (21.7) | 19 (27.5) | 21 (30.4) | 0.148 |
ABI* | 1.15 ± 0.11 | 1.19 ± 0.12 | 1.18 ± 0.13 | 1.16 ± 0.11 | <0.001 |
PWV (m/s) | 9.31 ± 2.32 | 9.33 ± 2.64 | 9.68 ± 2.37 | 9.48 ± 2.47 | 0.661 |
Renal | |||||
Serum creatinine (mg/dL) | 0.95 ± 0.14 | 0.97 ± 0.18 | 0.93 ± 0.17 | 0.96 ± 0.18 | 0.110 |
eGFR (mL/min/1.73 m2) | 89.5 ± 16.8 | 88.5 ± 18.3 | 92.3 ± 19.8 | 87.9 ± 18.2 | 0.072 |
Albumin/creatinine ratio (mg/g) | 34.8 ± 81.4 | 44.0 ± 122.9 | 37.7 ± 113.8 | 45.9 ± 156.8 | 0.826 |
Heart | |||||
Cornell VDP (mm/ms) | 1487 ± 573 | 1538 ± 506 | 1515 ± 543 | 1458 ± 535 | 0.285 |
Sokolow (mm/ms)*§|| | 20.3 ± 5.9 | 18.7 ± 6.2 | 21.3 ± 6.6 | 20.4 ± 6.8 | <0.001 |
Women | Baseline (n = 41) | 1st year (n = 41) | 2nd year (n = 41) | 3rd year (n = 41) | p |
|---|---|---|---|---|---|
Vascular | |||||
C-MT average (mm)§ | 0.715 ± 0.092 | 0.728 ± 0.076 | 0.726 ± 0.099 | 0.754 ± 0.115 | 0.034 |
Plaques carotid, n (%)†§ | 3 (7.3) | 3 (7.3) | 6 (14.6) | 11 (26.8) | <0.001 |
ABI*†‡ | 1.07 ± 0.10 | 1.17 ± 0.09 | 1.18 ± 0.10 | 1.14 ± 0.09 | <0.001 |
PWV (m/s) | 9.74 ± 2.70 | 9.21 ± 2.11 | 9.14 ± 2.34 | 9.79 ± 2.92 | 0.286 |
Renal | |||||
Serum creatinine (mg/dL) | 0.73 ± 0.11 | 0.73 ± 0.12 | 0.70 ± 0.13 | 0.72 ± 0.14 | 0.285 |
eGFR (mL/min/1.73 m2) | 89.1 ± 16.6 | 93.2 ± 22.6 | 95.0 ± 16.6 | 93.1 ± 22.1 | 0.163 |
Albumin/creatinine ratio (mg/g) | 14.6 ± 37.4 | 6.6 ± 6.6 | 3.0 ± 5.6 | 9.1 ± 14.8 | 0.122 |
Heart | |||||
Cornell VDP (mm/ms) | 1741 ± 598 | 1756 ± 542 | 1852 ± 680 | 1838 ± 740 | 0.430 |
Sokolow (mm/ms)§ | 19.1 ± 6.1 | 19.4 ± 5.3 | 20.5 ± 5.6 | 19.6 ± 5.7 | 0.013 |