Table 1 Clinical and metabolic characteristics
From: Soluble RAGE and atherosclerosis in youth with type 1 diabetes: a 5-year follow-up study
Baseline | 5 year follow-up | |||||
|---|---|---|---|---|---|---|
Diabetes (n = 299) | Controls (n = 112) | p value | Diabetes (n = 241) | Controls (n = 128) | p value | |
Diabetes duration (years)a | 5.1 (2.9, 7.7) | 9.6 (7.5, 12.6) | ||||
Insulin pump users (%) | 53.3 | 61.3 | ||||
Age (years) | 13.7 (2.8) | 13.4 (2.5) | 0.207 | 18.7 (2.8) | 18.7 (2.9) | 0.895 |
Girls, n (%) | 150 (50.2) | 64 (57.1) | 0.224 | 129 (53.5) | 72 (56.3) | 0.661 |
Height (cm) | 160.5 (14.4) | 157.6 (13.3) | 0.060 | 171.2 (9.1) | 172.1 (9.2) | 0.383 |
Weight (kg) | 54.8 (16.7) | 48.5 (13.2) | <0.001 | 71.0 (14.6) | 66.9 (12.5) | 0.006 |
BMI (kg/m2) | 20.8 (3.9) | 19.2 (3.1) | <0.001 | 24.1 (4.3) | 22.5 (3.4) | <0.001 |
Waist circumference (cm) | 71.1 (10.0) | 66.8 (6.6) | <0.001 | 79.0 (9.6) | 75.5 (8.2) | <0.001 |
Systolic blood pressure (mmHg) | 101 (10.1) | 98 (10) | 0.025 | 112 (11) | 111 (10) | 0.656 |
Diastolic blood pressure (mmHg) | 60 (8) | 58 (7) | 0.017 | 70 (8) | 68 (8) | 0.024 |
HbA1c (%) [mmol/mol, SD] | 8.4 (1.2) [68, 13.1] | 5.3 (0.3) [34, 3.3] | <0.001 | 9.0 (1.4) [75, 15.3] | 5.2 (0.3) [33, 3.3] | <0.001 |
Total cholesterol (mmol/L) | 4.6 (0.8) | 4.3 (0.7) | 0.001 | 4.8 (1.0) | 4.4 (1.0) | 0.001 |
HDL (mmol/L) | 1.8 (0.4) | 1.7 (0.4) | 0.048 | 1.6 (0.5) | 1.6 (0.4) | 0.161 |
LDL (mmol/L) | 2.5 (0.7) | 2.3 (0.7) | 0.016 | 2.7 (0.8) | 2.5 (0.8) | 0.014 |
Triglycerides (mmol/L)a | 0.7 (0.5, 0.9) | 0.7 (0.5, 0.9) | 0.367 | 0.9 (0.6, 1.3) | 0.8 (0.6, 1.0) | 0.024 |
Apolipoprotein B (g/L) | 0.74 (0.19) | 0.66 (0.17) | <0.001 | 0.90 (0.26) | 0.79 (0.23) | <0.001 |
Apolipoprotein A1 (g/L) | 1.55 (0.28) | 1.44 (0.33) | 0.001 | 1.56 (0.31) | 1.48 (0.27) | 0.006 |
ApoB/ApoA1 | 0.5 (0.2) | 0.5 (0.3) | 0.698 | 0.6 (0.2) | 0.5 (0.2) | 0.025 |
Urine albumin/creatinine (mg/mmol)a | 0.70 (0.40, 1.30) | 0.63 (0.36, 1.33) | 0.688 | 0.65 (0.30, 1.55) | 0.34 (0.19, 0.90) | 0.001 |