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Table 2 Comparison of MRI metrics between the four groups

From: Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

 

Group 1 CVD+ DM+

Group 2 CVD− DM+

Group 3 CVD+ DM−

Group 4 CVD− DM−

p value

WB-MRA

 WB SAS

4 (0–41.1)**

3.23 (0–19.4)

10.1 (0–39.5)**

2.4 (0–19.4)

<0.001

 Head/neck-SAS

5.6 (0–11.8)^

2.8 (2.8–5.6)

5.6 (2.8–9.0)

0 (0–5.6)

0.024

 Aorta-SAS

8.3 (0–16.7)

0 (0–8.3)

16.7 (8.3–16.7)**

8.3 (0–8.3)

<0.001

 Abdomen-SAS

0 (0–10)

0 (0–5)

5 (0–15)*

0 (0–10)

0.02

 Ilio-femoral-SAS

4.2 (0–22.9)*

4.2 (0–8.3)

18.8 (4.2–30.2)**

0 (0-10.4)

<0.001

 Run off-SAS

4.7 (0–19.5)**

0 (0–3.1)

3.1 (0–25.8)**

0 (0–1.6)

<0.001

 Normal vessels

765**

1432

627**

779

<0.001

 Vessels with 1–50 % stenosis

190

251

221**

107

0.008

 Vessels with 51–70 % stenosis

38**

7

24*

6

<0.001

 Vessels with 71–99 % stenosis

24*

4

26**

6

0.002

 Occluded vessels

22

4

30**

1

<0.001

 Abnormal vessels

8.5**

5

10.1**

4.1

<0.001

 N (%) with >50 % stenosis in any vessel

19 (56 %)**

12 (21.8 %)

20 (66.7 %)**

11 (38 %)

<0.001

Cardiac MRI

 LVM (g/m2)

60.5 (45–86)**

54.4 (39–95)

60 (41–86)**

50.9 (35–73)

0.001

 LVEDV (ml/m2)

71.2 ± 14.5

66.9 ± 12.8

74.9 ± 19.8

68.7 ± 9.9

0.096

 LVESV (ml/m2)

24.4 (9–58)

22.4 (11–55)

25.1 (11–90)

24.9 (13–38)

0.52

 LVEF (%)

64.6 ± 11.3

65.9 ± 8.8

64.3 ± 10.3

66 ± 7.4

0.83

 LVSV (ml/m2)

45.3 ± 9.2

43.7 ± 8.2

47 ± 8.2

45.1 ± 7.2

0.37

 LVMVR (g/ml)

0.88 ± 0.14^

0.84 ± 0.13

0.83 ± 0.16

0.78 ± 0.14

0.036

 LVGFI

0.43 ± 0.09

0.45 ± 0.08

0.44 ± 0.08

0.47 ± 0.07

0.21

 LGE (%)

9 (29)*

3 (5.5)

11 (38)*

0 (0)

<0.001

  1. Values expressed as mean ± SD, median (range) or N (%)
  2. Group 1, T2DM and CVD; Group 2, T2DM, no CVD; Group 3, CVD; Group 4, healthy volunteers
  3. SAS standardised atheroma score, WB whole body, LVM left ventricular massa, EDV end diastolic volumea, ESV end systolic volumea, EF ejection fraction, SV stroke volumea, LVMVR left ventricular mass volume ratio, LVGFI left ventricular global function index, LGE late gadolinium enhancement
  4. * p < 0.05 when compared to Group 2
  5. ** p < 0.05 when compared to Groups 2 and 4
  6. ^p < 0.05 when compared to Group 4
  7. aNormalised to body surface area