Skip to main content

Table 1 Baseline characteristics of patients in the ITT safety population

From: Long-term changes in cardiovascular risk markers during administration of exenatide twice daily or glimepiride: results from the European exenatide study

 

Exenatide twice daily (n = 511)

Glimepiride (n = 508)

Age (year), mean (SD)*

56 (10)

57 (9)

Male/female (%)*

56/44

52/48

Body weight (kg), mean (SD)

92.6 (16.6)

90.9 (15.1)

BMI (kg/m2), mean (SD)

32.5 (4.2)

32.2 (4.0)

Waist circumference (cm), mean (SD)

108.3 (11.8)

107.6 (11.5)

Systolic blood pressure (mmHg), mean (SD)

132.9 (15.7)

133.6 (15.4)

Diastolic blood pressure (mmHg), mean (SD)

80.5 (9.4)

79.8 (10.1)

Heart rate (beats per minute), mean (SD)

74.0 (9.3)

74.0 (10.1)

A1C (%), mean (SD)*

7.5 (0.7)

7.4 (0.7)

A1C (mmol/mol), mean (SD)*

58 (7.7)

57 (7.7)

Total cholesterol (mmol/L), mean (SD)

4.7 (1.0)

4.7 (1.0)

LDL-cholesterol (mmol/L), mean (SD)

2.5 (0.8)

2.5 (0.8)

HDL-cholesterol (mmol/L), mean (SD)

1.3 (0.3)

1.3 (0.3)

Triglycerides (mmol/L), mean (SD)

1.9 (1.2)

2.0 (1.3)

High sensitivity C-reactive protein (mg/L), mean (SD)

4.8 (7.7)

4.2 (5.1)

Taking antihypertensive drugs (%)

65.4

70.3

Taking lipid-lowering drugs (%)

45.6

53.4

  1. * Age, sex, and A1C were measured for the ITT efficacy population only as per protocol, exenatide (n = 490), glimepiride (n = 487). BMI body mass index, HDL high-density lipoprotein, ITT intent-to-treat, LDL low-density lipoprotein, SD standard deviation