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Table 3 OR (95 % CI) by multiple logistic regression models for diabetes in relation to betatrophin and C-peptide

From: Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects

Models

Betatrophin (n = 749)

P-trend

C-peptide (n = 749)

P-trend

T1, n = 247, T2D = 19

T2, n = 253, T2D = 52

T3, n = 249, T2D = 143

T1, n = 249, T2D = 51

T2, n = 251, T2D = 69

T3, n = 249, T2D = 94

Model 1

1

3.1 (1.8–5.4)

16.2 (9.5–27.5)

<0.0001

1

1.5 (1.0–2.2)

2.4 (1.6–3.5)

0.0001

Model 2

1

1.9 (1.1–3.4)

7.6 (4.2–13.8)

<0.0001

1

1.2 (0.7–1.9)

1.6 (0.9–2.5)

0.1778

Model 3

1

1.8 (1.0–3.3)

7.3 (4.0–13.3)

<0.0001

1

1.1 (0.7–1.8)

1.3 (0.8–2.1)

0.6698

  1. Model 1 unadjusted; Model 2 adjusted for age, BMI, gender and ethnicity; Model 3 adjusted for betatrophin + C-peptide + Model 2
  2. Tertile values of C-peptide are expressed as T1 (<468.3), T2 (468.3–707.5), and T3 (>707.5). Tertile values of betatrophin are T1 (<743.24), T2 (743.2–1229.2), and T3 (>1229.2)