Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects

Table 2 Partial Spearman correlations between betatrophin levels and diabetes/metabolic risk factors

Variable	All		T2D		Non-diabetics
Variable	Betatrophin	C-peptide	Betatrophin	C-peptide	Betatrophin	C-peptide
Age	0.56 (<0.0001)	0.17 (<0.0001)	0.48 (<0.0001)	−0.02 (0.8049)	0.50 (<0.0001)	0.17 (<0.0001)
BMI	0.17 (<0.0001)	0.41 (<0.0001)	0.13 (0.0535)	0.31 (<0.0001)	0.13 (00.0018)	0.44 (<0.0001)
FBG	0.40 (<0.0001)	0.35 (<0.0001)	−0.02 (0.8231)	0.09 (0.1965)	0.19 (<0.0001)	0.35 (<0.0001)
Insulin	0.17 (<0.0001)	0.63 (<0.0001)	−0.03 (0.7059)	0.39 (<0.0001)	0.11 (0.0121)	0.72 (<0.0001)
Cpeptide	0.26 (<0.0001)		0.07 (0.3366)		0.28 (<0.0001)
Betatrophin		0.27 (<0.0001)		0.07 (0.3366)		0.28 (<0.0001)

Diabetes: fasting plasma glucose ≥7 mmol/L, under treatment, or self-reported of previously diagnosed T2D; waist/hip ratio. Duration of diabetes was calculated for subjects with diabetes. Partial Spearman correlation coefficients were adjusted for age, gender, and ethnicity
BMI body mass index, FBG fasting blood glucose

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