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Table 1 Clinical and biochemical profiles for non-diabetics and T2D subjects

From: Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects

Variables Normal (n = 535) T2D (n = 214) P value
Age (years) 41.3 ± 10.1 50.5 ± 9.8 <0.0001
Ethnicity
 Arab 285 (53.3 %) 110 (51.4 %)  
 South Asian 250 (46.7 %) 104 (49.6 %)  
BMI (kg/m2) 29.36 ± 6.23 30.72 ± 5.59 0.0039
Waist/hip ratio 0.91 ± 0.11 0.95 ± 0.06 <0.0001
Systolic (mmHg) 128.6 ± 17.9 138.7 ± 19.7 <0.0001
Diastolic (mmHg) 78.9 ± 12.2 81.4 ± 11.4 0.0083
FBG (mmol/L) 5.02 ± 0.58 8.91 ± 3.60 <0.0001
HBA1C (DCCT %) 5.47 ± 0.70 7.79 ± 2.09 <0.0001
Insulin (mU/L) 9.72 ± 6.23 20.43 ± 41.87 0.0003
HOMAIR 2.22 ± 1.60 8.03 ± 17.66 <0.0001
Total cholesterol (mmol/L) 5.17 ± 1.09 5.13 ± 1.07 0.5694
Triglycerides (mmol/L) 1.50 ± 0.87 2.04 ± 1.47 <0.0001
HDL cholesterol (mmol/L) 1.14 ± 0.33 1.06 ± 0.28 0.0022
LDL cholesterol (mmol/L) 3.40 ± 0.99 3.21 ± 0.94 0.0154
Betatrophin (pg/mL) 720.3 (59.5–9345.1) (1710.1 (197.4–10972.1) <0.0001
C peptide 606.2 ± 300.1 744.1 ± 419.0 <0.0001
  1. Results are reported as Mean ± SD except for non-normally distributed betatrophin that are presented as Median (range). Diabetes: fasting plasma glucose ≥ 7 mmol/l, under treatment, or self-reported of previously diagnosed T2D