Table 1 Clinical and biochemical profiles for non-diabetics and T2D subjects
From: Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects
Variables | Normal (n = 535) | T2D (n = 214) | P value |
|---|---|---|---|
Age (years) | 41.3 ± 10.1 | 50.5 ± 9.8 | <0.0001 |
Ethnicity | |||
 Arab | 285 (53.3 %) | 110 (51.4 %) |  |
 South Asian | 250 (46.7 %) | 104 (49.6 %) |  |
BMI (kg/m2) | 29.36 ± 6.23 | 30.72 ± 5.59 | 0.0039 |
Waist/hip ratio | 0.91 ± 0.11 | 0.95 ± 0.06 | <0.0001 |
Systolic (mmHg) | 128.6 ± 17.9 | 138.7 ± 19.7 | <0.0001 |
Diastolic (mmHg) | 78.9 ± 12.2 | 81.4 ± 11.4 | 0.0083 |
FBG (mmol/L) | 5.02 ± 0.58 | 8.91 ± 3.60 | <0.0001 |
HBA1C (DCCT %) | 5.47 ± 0.70 | 7.79 ± 2.09 | <0.0001 |
Insulin (mU/L) | 9.72 ± 6.23 | 20.43 ± 41.87 | 0.0003 |
HOMAIR | 2.22 ± 1.60 | 8.03 ± 17.66 | <0.0001 |
Total cholesterol (mmol/L) | 5.17 ± 1.09 | 5.13 ± 1.07 | 0.5694 |
Triglycerides (mmol/L) | 1.50 ± 0.87 | 2.04 ± 1.47 | <0.0001 |
HDL cholesterol (mmol/L) | 1.14 ± 0.33 | 1.06 ± 0.28 | 0.0022 |
LDL cholesterol (mmol/L) | 3.40 ± 0.99 | 3.21 ± 0.94 | 0.0154 |
Betatrophin (pg/mL) | 720.3 (59.5–9345.1) | (1710.1 (197.4–10972.1) | <0.0001 |
C peptide | 606.2 ± 300.1 | 744.1 ± 419.0 | <0.0001 |