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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells

Fig. 6

Comparison of the inhibitory effects of BMPER knockdown with rosuvastatin on high glucose-increased ALP activity. ALP activity of HCASMCs cultured with rosuvastatin, BMPER knockdown-HCASMCs, and BMPER knockdown-HCASMCs cultured with rosuvastatin was compared at day 10. Representative images of the ALP-staining (a) and percentages of the ALP-positive area relative to the total surface area of HCASMCs (b) are shown. The data are presented as mean ± SEM (n = 4). *P < 0.05; P < 0.01; ns not significant.

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