Comparison of the inhibitory effects of BMPER knockdown with rosuvastatin on high glucose-increased ALP activity. ALP activity of HCASMCs cultured with rosuvastatin, BMPER knockdown-HCASMCs, and BMPER knockdown-HCASMCs cultured with rosuvastatin was compared at day 10. Representative images of the ALP-staining (a) and percentages of the ALP-positive area relative to the total surface area of HCASMCs (b) are shown. The data are presented as mean ± SEM (n = 4). *P < 0.05; †
P < 0.01; ns not significant.