Fig. 7
Analysis of Akt/mTORC1 activity. Representative blots (left) and summary data (right) of Western blotting for phospho-Ser473 and total Akt (a), phospho-Ser2448 and total mTOR (b), and phospho-Ser235/236 and total S6 (c) in samples from sham-operated heats or the non-infarcted myocardium after MI in LETO and OLETF. Representative blots (left) and summary data (right) of Western blotting for phospho-Ser473 and total Akt (d), phospho-Ser2448 and total mTOR (e), and phospho-Ser235/236 and total S6 (f) in the non-infarcted myocardium after MI in OLETF treated with the vehicle, vildagliptin (Vilda), or exenatide (Exe). N = 9–10 in each group. *p < 0.05. a.u. arbitrary units.