Skip to main content
Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats

Fig. 4

Vildagliptin restored autophagic induction in the non-infarcted area after MI in OLETF. a Representative images of Western blotting for LC3 protein (left) and summary data of LC3-II level and LC3-II/LC3-I ratio (right) in samples from sham-operated hearts (Sham) or the non-infarcted myocardium after MI in LETO and OLETF. b Representative images of Western blotting for LC3 protein (left) and summary data of LC3-II level and LC3-II/LC3-I ratio (right) in samples from the non-infarcted myocardium after MI in OLETF treated with the vehicle, vildagliptin (Vilda), or exenatide (Exe). c Representative blots (left) and summary data (right) of Western blotting for p62 protein in samples from sham-operated hearts (Sham) or the non-infarcted myocardium after MI in LETO and OLETF. Representative blots (left and middle) and summary data (right) of Western blotting for p62 protein in OLETF treated with the vehicle, Vilda, or Exe after MI. N = 8–10 in each group. *p < 0.05. a.u. arbitrary units, NS not significant.

Back to article page