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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats

Fig. 3

Effects of vildagliptin, exenatide, and chloroquine on survival after MI. Kaplan–Meier survival analysis of LETO (a), OLETF (b), and rats treated with chloroquine (c) after left coronary artery occlusion. *p < 0.05 vs. Vehicle-treated group. Infarct size measured at 48 h after MI in LETO (d), OLETF (e), and rats treated with chloroquine (f). g Quantification of BNP mRNA levels normalized to β-actin in the non-infarcted myocardium sampled 12 h after MI. N = 3–6 in each group. h Summary data of immunoblotting for phospho-Ser157 VASP in samples from LETO, vehicle- or vildagliptin-treated OLETF after MI. N = 9–12 in each group. Vilda vildagliptin, Exe exenatide, CQ chloroquine.

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