| Study 1 (n = 12) | Study 2 (n = 10) |
---|---|---|
Clinical characteristics | ||
 Age (year) | 64.8 ± 7.0 | 66.1 ± 4.6 |
 Male sex | 11 (92) | 10 (100) |
 Type 2 diabetes | 0 | 10 (100) |
 Weight (kg) | 84 (10) | 93 (14) |
 BSA (m2) | 2.0 ± 0.1 | 2.2 ± 0.2 |
 HOMA IR | 1.3 ± 0.8 | 2.7 ± 1.3 |
 HbA1c, (%) | – | 7.0 ± 0.7 |
Coronary disease | ||
 LAD stenosis | 8 (67) | 6 (60) |
 LCx stenosis | 4 (33) | 2 (20) |
 RCA stenosis | 4 (33) | 7 (70) |
 Single vessel CAD | 8 (67) | 7 (70) |
 Two vessel CAD | 4 (33) | 1 (10) |
 Three vessel CAD | 0 | 2 (20) |
Anti-anginal medications | ||
 B-blocker | 11 (92) | 6 (60) |
 Calcium channel antagonist | 1 (8) | 7 (70) |
 Long-acting nitrate | 8 (67) | 3 (30) |
 Nicorandil | 0 | 4 (40) |
Oral hypoglycemic agents | ||
 Metformin | – | 4 (40) |
 Sulfonylurea | – | 4 (40) |
 Thiazolidinedione | – | 1 (10) |