| Control | Diabetic | Diabetic + fasudil |
---|
ESPVR (mmHg/μl) | 0.52 ± 0.15 | 0.28 ± 0.05 | 0.33 ± 0.01 |
PRSW (mmHg) | 74 ± 10 | 48 ± 4* | 63 ± 6 |
EDPVR (mmHg/μl) | 0.03 ± 0.005 | 0.02 ± 0.001 | 0.03 ± 0.005 |
dP/dt-EDV (mmHg/s/μl) | 23 ± 4 | 15 ± 1 | 22 ± 3 |
- Data expressed as mean ± SEM.
- ESPVR, end systolic pressure volume relationship; PRSW, preload recruitable stroke work; EDPVR, end diastolic pressure volume relationship; dP/dt-EDV, relationship of rate of pressure development and end diastolic volume.
- *Â PÂ <Â 0.05 vs. control.