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Table 1 General characteristics of rats from experiment 2

From: Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension

 

Control

Control + fasudil

Diabetic

Diabetic + fasudil

N

5

4

7

7

Body weight (g)

381 ± 6

384 ± 17

300 ± 20**

275 ± 17#

Fasted blood glucose (mmol/L)

7.3 ± 0.3

7.5 ± 0.1

28.5 ± 1.8##

32.3 ± 0.7##

Mean arterial pressure (mmHg)

95.8 ± 5.5

105.3 ± 9.2

83.9 ± 7.3

94.4 ± 10.9

Left ventricle weight (g)

0.76 ± 0.02

0.74 ± 0.03

0.66 ± 0.06

0.59 ± 0.04#

Left ventricle weight:body weight (mg/g)

2.0 ± 0.08

1.9 ± 0.04

2.3 ± 0.04

2.2 ± 0.13

  1. Data expressed as mean ± SEM.
  2. * P < 0.05, ** P < 0.01 and ##P < 0.0001 vs. control rats.