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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension

Figure 1

Rho kinase 1 (ROCK1) expression in the left ventricle. Representative images of western blot membranes for ROCK1 (a) and actin loading control (b) from control, diabetic and diabetic rats treated with fasudil (10 mg/kg/day). Compared to control rats, ROCK1 protein expression in the left ventricle of diabetic rats was similar. Fasudil treatment (10 mg/kg/day) in diabetic rats did not change ROCK1 expression in the left ventricle in comparison to the diabetic group. Panel c is the quantification of ROCK1 expression relative to actin. Data expressed as mean ± SEM. N = 6 per group.

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Cardiovascular Diabetology

ISSN: 1475-2840