Rutin administration attenuates myocardial dysfunction in diabetic rats

Table 3 Echocardiographic left ventricular functional data

Parameters	C (n = 14)	C-R (n = 14)	DM (n = 16)	DM-R (n = 16)
FS (%)	54.1 ± 5.2	52.5 ± 2.87	48.7 ± 3.4*	52.6 ± 4.2^§
PWSV (mm/s)	44.5 ± 4.6	44.3 ± 3.54	35.5 ± 5.4*	42.7 ± 4.6^§
E (cm/s)	74.1 ± 11.7	66.6 ± 10.2	75.1 ± 14.3	79.8 ± 12.2^#
A (cm/s)	52.9 ± 11.3	45.5 ± 8.82	48.1 ± 18.1	63.1 ± 21.8^#§
E/A	1.43 ± 0.23	1.51 ± 0.31	1.77 ± 0.82	1.36 ± 0.34^§

Data are expressed as mean ± standard deviation. One-way ANOVA in a factorial design 2 × 2 and Tukey’s post hoc test.
C untreated rats, C-R rutin-treated rats, DM untreated diabetic rats, DM-R rutin-treated diabetic rats, FS endocardial fractional shortening, PWSV posterior wall shortening velocity, E early diastolic mitral inflow velocity, A late diastolic mitral inflow velocity, E/A E/A ratio.
* p < 0.05 vs C; ^#p < 0.05 vs C-R; ^§p < 0.05 vs DM.

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