Table 7 Genes significantly up-regulated in control MVT-treated vs. control vehicle-treated group on DNA microarray

Metabolism

proline dehydrogenase (oxidase) 1

NM_001135778

Prodh

0.93 (0.50)

0.043

1.91

0.95 (0.48)

1.93

−0.27 (0.63)

−1.21

Metabolism

enolase 2, gamma, neuronal

NM_139325

Eno2

1.00 (0.30)

0.017

2.00

0.98^b (0.85)

1.97

−1.32^b (1.12)

−2.50

Metabolism

4-hydroxyphenylpyruvate dioxygenase

NM_017233

Hpd

1.00 (0.48)

0.034

2.01

1.07 (0.38)

2.09

−0.06 (0.34)

−1.04

Immune response

complement factor B

NM_212466

Cfb

0.85 (0.32)

0.025

1.80

0.14 (0.34)

1.10

0.22 (0.34)

1.17

Immune response

2’-5’ oligoadenylate synthetase 1A

NM_138913

Oas1a

0.92 (0.33)

0.020

1.90

0.40 (0.28)

1.32

−0.43 (0.24)

−1.35

Immune response

2-5 oligoadenylate synthetase 1B

AF068268

Oas1b

1.04 (0.18)

0.015

2.06

−0.52 (0.50)

−1.44

0.11 (0.83)

1.08

Immune response

2’-5’ oligoadenylate synthetase 1I

NM_001009680

Oas1i

0.87 (0.24)

0.018

1.83

0.13 (0.31)

1.09

−0.29 (0.22)

−1.22

Immune response

interferon regulatory factor 7

NM_001033691

Irf7

1.13 (0.27)

0.016

2.18

−0.05 (0.12)

−1.04

0.25 (0.20)

1.19

Immune response

complement component 4A (Rodgers blood group)

NM_031504

C4a

1.18 (0.39)

0.017

2.27

0.29 (0.44)

2.27

0.05 (0.34)

1.04

Immune response

hepcidin antimicrobial peptide

NM_053469

Hamp

1.38 (0.74)

0.040

2.60

0.59 (0.77)

1.51

−0.56 (0.74)

−1.47

Immune response

myxovirus (influenza virus) resistance 2

NM_134350

Mx2

2.14 (0.95)

0.020

4.41

0.42 (0.63)

1.34

−0.72 (0.67)

−1.65

Cell growth and differentiation

neuronatin

NM_053601

Nnat

0.99 (0.41)

0.025

1.98

0.73 (0.40)

1.66

−0.06 (0.74)

−1.04

Cell growth and differentiation

H19, imprinted maternally expressed transcript

NR_027324

H19

1.16 (0.44)

0.020

2.24

0.92 (0.49)

1.89

−0.53 (0.47)

−1.44

Receptors and ion channels

ATPase, H⁺/K⁺ exchanging, alpha polypeptide

NM_012509

Atp4a

0.86 (0.19)

0.017

1.81

0.45 (0.48)

1.37

−0.05 (0.59)

−1.04

Receptors and ion channels

sarcolipin

NM_001013247

Sln

1.09 (0.61)

0.043

2.13

1.07 (0.61)

2.10

−0.23 (0.42)

−1.17

Receptors and ion channels

ATPase, Na⁺/K⁺ transporting, beta 4 polypeptide

NM_053381

Atp1b4

1.14 (0.63)

0.043

2.21

0.41 (0.64)

1.33

0.04 (0.81)

1.03

Others

2’-5’ oligoadenylate synthetase-like 2

NM_001009682

Oasl2

0.96 (0.34)

0.020

1.95

−0.21 (0.19)

−1.15

0.08 (0.14)

1.05

Others

GRAM domain containing 3

NM_001014011

Gramd3

0.97 (0.31)

0.018

1.96

−0.03 (0.41)

−1.02

0.36 (0.79)

1.29