Diabetes Vehicle | Diabetes MVT | Control MVT | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
vs. | vs. | vs. | ||||||||
Control Vehicle | Diabetes Vehicle | Control Vehicle | ||||||||
Gene function | Gene Name provided by RGD a | Acc. Number | Gene Symbol | Log2 (SD) | Corr. p | Fold change | Log2 (SD) | Fold Change | Log2 (SD) | Fold Change |
Metabolism | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 | NM_001109492 | B3galt2 | -1.14 (0.19) | 0.003 | -2.21 | 0.80 (0.49) | 1.74 | -0.16 (0.60) | -1.11 |
Metabolism | adenylate kinase 4 | NM_017135 | Ak4 | -0.99 (0.49) | 0.026 | -1.99 | 0.76 (0.40) | 1.70 | -0.47 (0.70) | -1.38 |
Stress response | APEX (apurinic/apyrimidinic) endonuclease 2 | NM_001079892 | Apex2 | -0.94 (0.56) | 0.042 | -1.92 | 0.09 (0.26) | 1.06 | -1.18 (0.63) | -2.26 |
Apoptosis/necrosis and inflammation | caspase recruitment domain family, member 9 | NM_022303 | Card9 | -2.74 (0.64) | 0.003 | -6.69 | 1.82 (0.52) | 3.53 | -1.20b (0.88) | -2.29 |
Apoptosis/necrosis and inflammation | chemokine (C-X-C motif) ligand 12 | NM_001033883 | Cxcl12 | -0.86 (0.38) | 0.021 | -1.82 | 0.48 (0.40) | 1.40 | 0.06 (0.30) | 1.04 |
Cell growth and differentiation | neuronal regeneration related protein | NM_178096 | Nrep | -1.11 (0.55) | 0.023 | -2.46 | 0.50 (0.49) | 1.41 | -1.46b (1.36) | -2.74 |
Cell growth and differentiation | HOP homeobox | NM_133621 | Hopx | -1.14 (0.52) | 0.020 | -2.20 | 0.60 (0.49) | 1.51 | -0.28 (0.71) | -1.21 |
Cell growth and differentiation | fibroblast growth factor 18 | NM_019199 | Fgf18 | -1.12 (0.53) | 0.021 | -2.17 | 0.80 (0.57) | 1.74 | -0.51 (0.23) | -1.43 |
Cell growth and differentiation | ret proto-oncogene | NM_012643 | Ret | -1.04 (0.14) | 0.003 | -2.06 | 0.63 (0.39) | 1.55 | -0.63 (0.15) | -1.55 |
Cell growth and differentiation | G0/G1 switch 2 | NM_001009632 | G0s2 | -0.86 (0.21) | 0.007 | -1.82 | 0.58 (0.47) | 1.50 | 0.26 (0.91) | 1.20 |
Receptors and ion channels | adrenoceptor alpha 1D | NM_024483 | Adra1d | -1.21 (0.52) | 0.016 | -2.31 | 1.12 (0.40) | 2.17 | -1.03b (1.36) | -2.04 |
Receptors and ion channels | FXYD domain-containing ion transport regulator 3 | NM_172317 | Fxyd3 | -1.01 (0.49) | 0.023 | -2.01 | 1.97 (0.48) | 3.92 | -0.36 (0.85) | -1.29 |
Receptors and ion channels | sodium channel, voltage-gated, type IV, beta | NM_001008880 | Scn4b | -0.94 (0.30) | 0.011 | -1.92 | 0.38 (0.15) | 1.30 | -0.43 (0.49) | -1.35 |
Receptors and ion channels | transferrin receptor | NM_022712 | Tfrc | -0.87 (0.21) | 0.007 | -1.83 | 0.09 (0.20) | 1.06 | -0.55 (0.32) | -1.46 |
Structural protein, cell adhesion | myosin binding protein C, fast-type | NM_001106257 | Mybpc2 | -0.93 (0.47) | 0.026 | -1.90 | 0.33 (0.52) | 1.25 | 0.48 (0.82) | 1.40 |
Structural protein, cell adhesion | protocadherin 17 | NM_001107279 | Pcdh17 | -0.94 (0.44) | 0.023 | -1.91 | 0.90 (0.43) | 1.86 | -0.65 (0.43) | -1.57 |
Hormones | inhibin alpha | NM_012590 | Inha | -0.89 (0.39) | 0.020 | -1.85 | 1.59 (0.79) | 3.01 | 0.66 (0.21) | 1.58 |
Transport | globin, alpha | NM_001013853 | LOC287167 | -1.64 (0.72) | 0.015 | -3.12 | -0.23 (0.81) | -1.18 | -1.80 (0.76) | -3.47 |
Transport | haemoglobin, beta adult major chain | NM_198776 | Hbb-b1 | -1.94 (0.75) | 0.011 | -3.83 | -0.40 (0.77) | -1.32 | -2.23 (0.76) | -4.71 |
Transport | alpha-2u globulin PGCL5 | NM_147213 | LOC259245 | -0.87 (0.54) | 0.047 | -1.83 | -0.03 (0.48) | -1.02 | -0.12 (0.58) | -1.08 |
Others | uncharacterized LOC100909684 | XR_146107 | LOC10099684 | -3.07 (1.43) | 0.016 | -8.43 | 2.55 (1.40) | 5.85 | -0.42 (0.76) | -1.34 |
Others | uncharacterized LOC100910110 | XR_146304 | LOC100910110 | -1.94 (0.32) | 0.003 | -3.85 | 2.32 (0.31) | 5.01 | -0.46 (1.57) | -1.38 |