Table 6 Changes in hemodynamic and echocardiographic parameters in the sitagliptin and voglibose group

SBP, mmHg

Baseline at 0W

135 ± 16

131 ± 13

0.180

At 24W

128 ± 10

129 ± 15

0.855

24W-0W

-7 ± 17

0.022

-2 ± 15

0.496

0.184

DBP, mmHg

Baseline at 0W

74 ± 13

75 ± 10

0.818

At 24W

71 ± 10

75 ± 11

0.108

24W-0W

-2 ± 14

0.344

1 ± 10

0.779

0.349

Pulse, b.p.m.

Baseline at 0W

71 ± 11

71 ± 10

0.903

At 24W

69 ± 12

71 ± 11

0.483

24W-0W

-1 ± 12

0.653

0 ± 12

0.816

0.625

Body weight

Baseline at 0W

69 ± 10

67 ± 12

0.294

At 24W

68 ± 11

67 ± 13

0.736

24W-0W

-1.3 ± 3.2

0.018

0.4 ± 2.8

0.433

0.020

a’, cm/s

Baseline at 0W

8.4 ± 1.6

9.0 ± 1.6

0.110

At 24W

8.1 ± 1.8

9.0 ± 1.6

0.031

24W-0W

-0.3 ± 1.7

0.316

0.2 ± 1.4

0.468

0.214

s’, cm/s

Baseline at 0W

6.6 ± 1.1

7.2 ± 1.2

0.019

At 24W

6.8 ± 1.4

7.0 ± 1.1

0.609

24W-0W

0.2 ± 1.4

0.398

-0.2 ± 1.4

0.412

0.237

Dct

Baseline at 0W

234 ± 41

237 ± 39

0.769

At 24W

236 ± 42

233 ± 43

0.765

24W-0W

1 ± 41

0.885

-4 ± 35

0.525

0.604

E velocity, m/s

Baseline at 0W

68 ± 16

62 ± 11

0.048

At 24W

69 ± 14

63 ± 14

0.047

24W-0W

1 ± 10

0.569

0 ± 12

0.879

0.803

A velocity, m/s

Baseline at 0W

82 ± 19

79 ± 18

0.421

At 24W

80 ± 19

74 ± 14

0.150

24W-0W

-1 ± 13

0.537

-4 ± 10

0.020

0.299

E/A ratio

Baseline at 0W

0.9 ± 0.3

0.8 ± 0.2

0.424

At 24W

0.9 ± 0.2

0.9 ± 0.3

0.668

24W-0W

0.0 ± 0.2

0.402

0.0 ± 0.2

0.157

0.651

Septal thickness, mm

Baseline at 0W

1.0 ± 0.2

0.9 ± 0.1

0.069

At 24W

0.9 ± 0.1

0.9 ± 0.1

0.502

24W-0W

0.0 ± 0.1

0.015

0.0 ± 0.1

0.876

0.083

LVEF, %

Baseline at 0W

68 ± 7

71 ± 7

0.209

At 24W

68 ± 6

66 ± 9

0.179

24W-0W

0 ± 8

0.967

-5 ± 8

0.001

0.013

LVMI, g/m2

Baseline at 0W

93 ± 20

85 ± 18

0.085

At 24W

90 ± 17

86 ± 18

0.239

24W-0W

-3 ± 13

0.195

1 ± 14

0.551

0.183

LA volume index, ml/m2

Baseline at 0W

27.7 ± 5.9

26.1 ± 7.6

0.346

At 24W

27.7 ± 7.5

26.6 ± 6.3

0.508

24W-0W

0.3 ± 5.0

0.734

0.8 ± 5.6

0.448

0.733

Urine albumin, mg/g/Cr

Baseline at 0W

37 ± 66

31 ± 41

0.603

At 24W

39 ± 94

28 ± 50

0.533

24W-0W

-1 ± 50

0.889

-5 ± 30

0.339

0.723

BUN

Baseline at 0W

17 ± 5

16 ± 5

0.760

At 24W

16 ± 3

16 ± 4

0.824

24W-0W

0 ± 3

0.759

0 ± 4

0.740

0.959