Variable | Sitagliptin | Voglibose | Between-group difference | ||
---|---|---|---|---|---|
 | Mean ± SD | P value | Mean ± SD | P value | P value |
Glucose | Â | Â | Â | Â | Â |
Baseline at 0W | 145 ± 58 |  | 133 ± 42 |  | 0.304 |
At 24W | 127 ± 26 |  | 133 ± 27 |  | 0.354 |
24W-0W | -23 ± 60 | 0.047 | 1 ± 43 | 0.916 | 0.083 |
HbA1c | Â | Â | Â | Â | Â |
Baseline at 0W | 7.1 ± 0.7 |  | 6.9 ± 0.5 |  | 0.273 |
At 24W | 6.4 ± 0.4 |  | 6.7 ± 0.5 |  | 0.026 |
24W-0W | -0.7 ± 0.6 | <0.0001 | -0.3 ± 0.4 | 0.0004 | 0.002 |
GIP | Â | Â | Â | Â | Â |
Baseline at 0W | 191 ± 214 |  | 159 ± 211 |  | 0.517 |
At 24W | 149 ± 161 |  | 162 ± 148 |  | 0.759 |
24W-0W | -21 ± 226 | 0.314 | 0.6 ± 1.6 | 0.041 | 0.749 |
CD34 | Â | Â | Â | Â | Â |
Baseline at 0W | 1.1 ± 0.7 |  | 0.9 ± 0.6 |  | 0.239 |
At 24W | 1.1 ± 0.5 |  | 0.9 ± 0.7 |  | 0.160 |
24W-0W | 0.1 ± 0.5 | 0.435 | 0.0 ± 0.5 | 0.772 | 0.430 |
Total cholesterol | Â | Â | Â | Â | Â |
Baseline at 0W | 184 ± 27 |  | 185 ± 33 |  | 0.944 |
At 24W | 178 ± 29 |  | 183 ± 37 |  | 0.522 |
24W-0W | -3 ± 30 | 0.603 | 0 ± 29 | 0.991 | 0.709 |
Triglyceride | Â | Â | Â | Â | Â |
Baseline at 0W | 155 ± 107 |  | 141 ± 74 |  | 0.486 |
At 24W | 132 ± 62 |  | 127 ± 72 |  | 0.803 |
24W-0W | -15 ± 94 | 0.391 | -13 ± 52 | 0.190 | 0.905 |
HDL-C | Â | Â | Â | Â | Â |
Baseline at 0W | 51 ± 12 |  | 56 ± 16 |  | 0.106 |
At 24W | 52 ± 14 |  | 53 ± 15 |  | 0.930 |
24W-0W | 0.8 ± 7.9 | 0.551 | -3.6 ± 8.2 | 0.010 | 0.021 |
Adiponectin | Â | Â | Â | Â | Â |
Baseline at 0W | 11.0 ± 8.3 |  | 13.3 ± 8.7 |  | 0.222 |
At 24W | 11.7 ± 8.8 |  | 12.9 ± 7.3 |  | 0.528 |
24W-0W | 0.5 ± 1.8 | 0.092 | -0.3 ± 2.9 | 0.539 | 0.150 |
MDA-LDL | Â | Â | Â | Â | Â |
Baseline at 0W | 106 ± 34 |  | 110 ± 37 |  | 0.658 |
At 24W | 113 ± 34 |  | 109 ± 36 |  | 0.591 |
24W-0W | 9 ± 32 | 0.118 | 1 ± 38 | 0.860 | 0.364 |
8-OHdG | Â | Â | Â | Â | Â |
Baseline at 0W | 11.7 ± 7.9 |  | 13.5 ± 10.0 |  | 0.392 |
At 24W | 11.4 ± 7.4 |  | 14.8 ± 14.6 |  | 0.221 |
24W-0W | -0.2 ± 10.0 | 0.903 | 1.5 ± 16.9 | 0.596 | 0.605 |
hs-CRP | Â | Â | Â | Â | Â |
Baseline at 0W | 3869 ± 9072 |  | 1358 ± 2511 |  | 0.099 |
At 24W | 1933 ± 5101 |  | 661 ± 691 |  | 0.147 |
24W-0W | -1929 ± 6798 | 0.098 | -380 ± 1186 | 0.059 | 0.186 |
PTX-3 | Â | Â | Â | Â | Â |
Baseline at 0W | 1.8 ± 1.0 |  | 2.4 ± 2.7 |  | 0.206 |
At 24W | 1.5 ± 0.8 |  | 1.6 ± 0.8 |  | 0.557 |
24W-0W | -0.3 ± 0.7 | 0.006 | -0.3 ± 1.2 | 0.104 | 0.974 |
e-GFR | Â | Â | Â | Â | Â |
Baseline at 0W | 75 ± 22 |  | 71 ± 15 |  | 0.304 |
At 24W | 69 ± 19 |  | 72 ± 16 |  | 0.411 |
24W-0W | -5 ± 12 | 0.014 | 0 ± 9 | 0.903 | 0.036 |
BNP, pg/ml | Â | Â | Â | Â | Â |
Baseline at 0W | 39 ± 48 |  | 34 ± 35 |  | 0.600 |
At 24W | 40 ± 41 |  | 28 ± 24 |  | 0.160 |
24W-0W | 1 ± 40 | 0.923 | -5 ± 22 | 0.164 | 0.443 |