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Table 3 Factors affecting e’ and E/e’ at week 24a

From: Comparison of effects of sitagliptin and voglibose on left ventricular diastolic dysfunction in patients with type 2 diabetes: results of the 3D trial

Dependent variable Independent variable Estimate 95 % CI P value
e’ (24W) e’ (0W) 0.525 0.309 0.742 <0.0001
Sitagliptin/Voglibose -0.047 -0.455 0.362 0.821
Age — yr -0.028 -0.054 -0.003 0.032
without/with TZD 0.547 0.130 0.965 0.011
E/e’ (24W) E/e’ (0W) 0.615 0.471 0.758 <0.0001
Sitagliptin/Voglibose 0.688 -0.239 1.615 0.144
Age — yr 0.024 -0.025 0.072 0.334
without/with TZD -1.411 -2.339 -0.483 0.003
  1. 95 % CIs and P values were calculated with the use of analysis of covariance (ANCOVA)
  2. aCI denotes confidence interval