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Fig. 7 | Cardiovascular Diabetology

Fig. 7

From: Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice

Fig. 7

FGF21 administration reversed pathologic changes in the aorta of FGF21KO DM mice. In a type 1 diabetes model, FGF21 administration reversed aortic thickening (a), fibrosis (b) and cell apoptosis (c) in the aorta of FGF21KO DM mice. Data are presented as means ± SD, n ≥ 5 for each group. * p < 0.05 vs WT Ctrl group; #: P < 0.05 vs. FGF21KO Ctrl; @: P < 0.05 vs. FGF21KO DM; $: P < 0.05 vs. WT DM. Bar = 50 μm. Abbreviations are the same as the Fig. 1. FGF21KO DM + FGF21: FGF21KO DM mice received FGF21 administration

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Cardiovascular Diabetology

ISSN: 1475-2840