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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice

Fig. 2

FGF21 deletion accelerated and aggravated diabetes-induced aortic fibrosis. At indicated time points after diabetes onset, aortic fibrosis was evaluated by Sirius Red staining of collagen accumulation (a, b) and immunohistochemical staining of CTGF expression (c, d). Data are presented as means ± SD, n ≥ 5 for each group. * p < 0.05 vs WT Ctrl group; # p < 0.05 vs FGF21KO Ctrl group; & p < 0.05 vs WT DM group. Bar = 50 μm. Abbreviations are the same as the Fig. 1

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Cardiovascular Diabetology

ISSN: 1475-2840