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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Chronic NF-κB blockade improves renal angiotensin II type 1 receptor functions and reduces blood pressure in Zucker diabetic rats

Fig. 6

Effect of PDTC on NF-κB signaling in the renal cortex of LZ and ZDF rats. LZ or ZDF rats were treated with PDTC (150 mg · kg body wt-1 · day-1) or vehicle for 4 weeks. a: Phosphorylation and expression of IKK and IκBα were determined by Western blot, and data were normalized using GAPDH expression. Nuclear and cytosol protein were prepared from the renal cortex and the expression of NF-κB in nuclear (Nu) (b) and cytosol (Cyto) (c) fractions were determined by Western blot. * P <0.05 vs LZ control; # P < 0.05 vs ZDF control (n = 5)

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Cardiovascular Diabetology

ISSN: 1475-2840