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Table 1 Biometric and biochemical parameters

From: Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice

Phenotypic variables

N-mock

N-CD36

O-mock

O-CD36

Body weight (g)

27.00 ± 1.00

26.90 ± 0.97

33.30 ± 0.95*a

32.80 ± 0.89*a

Alanine aminotransferase (U/L)

31.00 ± 2.93

33.25 ± 3.73

33.25 ± 3.96

34.50 ± 4.63

Aspartate transaminase (U/L)

112.00 ± 20.67

116.75 ± 19.02

118.38 ± 12.83

118.13 ± 14.75

Alkaline phosphatase (U/L)

86.25 ± 17.39

92.50 ± 8.77

104.25 ± 11.85

100.75 ± 14.75

Albumin (g/L)

27.75 ± 1.06

28.70 ± 1.04

25.70 ± 1.55*a

26.63 ± 1.54a

Blood urea nitrogen (mmol/L)

11.10 ± 0.34

12.51 ± 1.37

13.66 ± 2.25*

10.44 ± 2.31b

Creatinine (μmol/L)

10.75 ± 0.46

12.50 ± 1.77

14.38 ± 3.42*

10.13 ± 1.96b

Fasting serum glucose (mmol/L)

4.93 ± 0.29

4.76 ± 1.26

6.63 ± 1.84*a

6.42 ± 1.32*a

Total cholesterol (mmol/L)

2.01 ± 0.11

2.15 ± 0.13

4.74 ± 0.84*a

4.64 ± 0.79*a

Triglyceride (mmol/L)

0.92 ± 0.14

0.85 ± 0.09

2.38 ± 1.38*a

1.77 ± 0.66

  1. Values are mean ± SD, N = 8-10 for each group
  2. a P < 0.05 vs. N-CD36
  3. b P < 0.05 vs. O-mock
  4. * P < 0.05 vs. N-mock