| |
CAN score category†
|
|---|
| |
Univariate OR (95 % CI)
|
p value
|
Multivariate OR (95 % CI)
|
p value
|
|---|
|
Short-term GV
| | | | |
|
SD of glucose
|
1.03 (1.01–1.06)
|
0.007
|
1.02 (0.99–1.05)
|
0.191
|
|
MAGE
|
1.01 (1.00–1.02)
|
0.059
|
1.01 (0.99–1.02)
|
0.398
|
|
CV of glucose
|
1.05 (1.00–1.10)
|
0.039
|
1.05 (1.00–1.10)
|
0.079
|
|
Long-term GV
| | | | |
|
SD of HbA1c
|
13.79 (4.43–42.89)
|
<0.001
|
15.40 (4.56–52.01)
|
<0.001
|
|
Adjusted SD of HbA1c
|
18.83 (5.31–66.80)
|
<0.001
|
17.46 (3.86–79.06)
|
<0.001
|
|
Log CV of HbA1c
|
29.23 (5.47–156.11)
|
<0.001
|
27.21 (4.28–172.91)
|
<0.001
|
-
†CAN scores were categorized into 0–1.5 points (n = 62), 2–2.5 points (n = 33), and 3–5 points (n = 15)
- Multivariate model was adjusted for age, sex, duration of diabetes, mean HbA1c, use of insulin, use of oral anti-diabetic drug, use of aspirin, use of beta-blocker, use of ARB/ACE inhibitor and smoking status
-
CAN cardiovascular autonomic neuropathy, SD standard deviation, MAGE mean amplitude of glycemic excursions, CV coefficient of variance
