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Table 5 Ordinary logistic regression analysis for the associations between parameters of glycemic variability and the severity of CAN

From: The association between glycemic variability and diabetic cardiovascular autonomic neuropathy in patients with type 2 diabetes

 

CAN score category†

 

Univariate OR (95 % CI)

p value

Multivariate OR (95 % CI)

p value

Short-term GV

    

  SD of glucose

1.03 (1.01–1.06)

0.007

1.02 (0.99–1.05)

0.191

  MAGE

1.01 (1.00–1.02)

0.059

1.01 (0.99–1.02)

0.398

  CV of glucose

1.05 (1.00–1.10)

0.039

1.05 (1.00–1.10)

0.079

Long-term GV

    

  SD of HbA1c

13.79 (4.43–42.89)

<0.001

15.40 (4.56–52.01)

<0.001

  Adjusted SD of HbA1c

18.83 (5.31–66.80)

<0.001

17.46 (3.86–79.06)

<0.001

  Log CV of HbA1c

29.23 (5.47–156.11)

<0.001

27.21 (4.28–172.91)

<0.001

  1. †CAN scores were categorized into 0–1.5 points (n = 62), 2–2.5 points (n = 33), and 3–5 points (n = 15)
  2. Multivariate model was adjusted for age, sex, duration of diabetes, mean HbA1c, use of insulin, use of oral anti-diabetic drug, use of aspirin, use of beta-blocker, use of ARB/ACE inhibitor and smoking status
  3. CAN cardiovascular autonomic neuropathy, SD standard deviation, MAGE mean amplitude of glycemic excursions, CV coefficient of variance
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Cardiovascular Diabetology

ISSN: 1475-2840