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Table 3 The comparison of parameters of glycemic variability between hypoglycemic patients with and without cardiovascular autonomic neuropathy

From: The association between glycemic variability and diabetic cardiovascular autonomic neuropathy in patients with type 2 diabetes

  Over two episodes of hypoglycemia in CGM data (n = 40)
  No CAN (n = 29) CAN (n = 11) p value
CGM parameters    
  SD in glucose (mg/dL) 42.0 ± 14.9 55.0 ± 19.6 0.029
  MAGE (mg/dL) 94.5 ± 38.7 105.4 ± 37.7 0.424
  CV in glucose (%) 30.5 ± 8.4 35.7 ± 7.2 0.074
Mean glucose in CGM (mg/dL) 137.1 ± 35.2 151.5 ± 38.1 0.264
HbA1c variability    
  SD of HbA1c (%) 0.4 ± 0.2 0.6 ± 0.3 0.003
  Adjusted SD of HbA1c (%) 0.4 ± 0.2 0.6 ± 0.2 0.003
  CV of HbA1c 0.05 ± 0.02 0.08 ± 0.03 0.012
Mean HbA1c over 2 years (%) 7.3 ± 1.0 8.2 ± 1.0 0.019
  1. Data are mean ± SD
  2. CAN cardiovascular autonomic neuropathy, CGM continuous glucose monitoring, MAGE mean amplitude of glycemic excursions, SD standard deviation, CV coefficient of variance