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Table 2 The comparison of glycemic parameters between patients with and without cardiovascular autonomic neuropathy

From: The association between glycemic variability and diabetic cardiovascular autonomic neuropathy in patients with type 2 diabetes

  No CAN (n = 63) CAN (n = 47) p value
CGM parameters    
  SD of glucose (mg/dL) 41.6 ± 15.0 51.7 ± 17.2 0.001
  MAGE (mg/dL) 89.4 ± 37.1 103.1 ± 37.1 0.061
  CV of glucose (%) 25.9 ± 7.9 30.1 ± 8.1 0.002
Mean glucose in CGM (mg/dL) 162.6 ± 47.4 172.2 ± 42.7 0.275
HbA1c variability over 2 years    
 SD of HbA1c (%) 0.5 ± 0.3 0.8 ± 0.5 <0.001
  Adjusted SD of HbA1c (%) 0.4 ± 0.2 0.7 ± 0.4 <0.001
  CV of HbA1c 0.05 ± 0.04 0.09 ± 0.05 <0.001
Mean HbA1c over 2 years (%) 7.5 ± 1.0 8.4 ± 1.1 <0.001
  1. Data are mean ± SD
  2. Adjusted SD of HbA1c = SD of HbA1c/[n/(n–1)]0.5, where n is the number of HbA1c measurements
  3. CAN cardiovascular autonomic neuropathy, GV glycemic variability, CGM continuous glucose monitoring, MAGE mean amplitude of glycemic excursions, SD standard deviation, CV Coefficient of variance