|
No CAN (n = 63)
|
CAN (n = 47)
|
p value
|
---|
CGM parameters
| | | |
SD of glucose (mg/dL)
|
41.6 ± 15.0
|
51.7 ± 17.2
|
0.001
|
MAGE (mg/dL)
|
89.4 ± 37.1
|
103.1 ± 37.1
|
0.061
|
CV of glucose (%)
|
25.9 ± 7.9
|
30.1 ± 8.1
|
0.002
|
Mean glucose in CGM (mg/dL)
|
162.6 ± 47.4
|
172.2 ± 42.7
|
0.275
|
HbA1c variability over 2 years
| | | |
SD of HbA1c (%)
|
0.5 ± 0.3
|
0.8 ± 0.5
|
<0.001
|
Adjusted SD of HbA1c (%)
|
0.4 ± 0.2
|
0.7 ± 0.4
|
<0.001
|
CV of HbA1c
|
0.05 ± 0.04
|
0.09 ± 0.05
|
<0.001
|
Mean HbA1c over 2 years (%)
|
7.5 ± 1.0
|
8.4 ± 1.1
|
<0.001
|
- Data are mean ± SD
- Adjusted SD of HbA1c = SD of HbA1c/[n/(n–1)]0.5, where n is the number of HbA1c measurements
-
CAN cardiovascular autonomic neuropathy, GV glycemic variability, CGM continuous glucose monitoring, MAGE mean amplitude of glycemic excursions, SD standard deviation, CV Coefficient of variance