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Table 1 Demographic and clinical characteristics of patients by diabetic status and type of treatment

From: Diabetes mellitus and platelet reactivity in patients under prasugrel or ticagrelor treatment: an observational study

 

No diabetes mellitus

Diabetes mellitus non insulin-treated

Diabetes mellitus insulin-treated

p-value

N = 603

N = 132

N = 42

Male gender

519 (86.1)

116 (87.9)

38 (90.5)

0.7

Age (years)

58.9 ± 11.2

63.4 ± 10.4

62.8 ± 10.5

<0.001

Body mass index (Kg/m2)

28.1 ± 4.2

29.2 ± 4.5

29.2 ± 5.7

0.01

Dyslipidemia

300 (49.8)

72 (54.5)

19 (45.2)

0.5

Hypertension

286 (47.4)

94 (71.2)

21 (50.0)

<0.001

Current smoking

39 (6.5)

4 (3.0)

2 (4.8)

0.3

Prior myocardial infarction

45 (7.5)

10 (7.6)

4 (9.5)

0.8

Prior CABG

9 (1.5)

2 (1.5)

2 (4.8)

0.3

Prior PCI

58 (9.6)

12 (9.1)

4 (9.5)

1.0

Prior stroke/TIA

10 (1.7)

6 (4.5)

1 (2.4)

0.2

Admission for PCI

 

0.2

STEMI

342 (56.7)

63 (47.7)

26 (61.9)

 

NSTEMI

161 (26.7)

40 (30.3)

7 (16.7)

 

Unstable angina

100 (16.6)

29 (22.0)

9 (21.4)

 

Creatinine clearance <60 ml/min

51 (8.5)

18 (13.6)

11 (26.2)

0.001

P2Y12 receptor blocker at discharge and follow-up

0.7

Ticagrelor

363 (60.2)

76 (57.6)

23 (54.8)

 

Prasugrel

240 (39.8)

56 (42.4)

19 (45.2)

 

Other discharge medication*

Aspirin 100 mg

598 (99.2)

131 (99.2)

42 (100)

1.0

Statin

595 (98.7)

128 (97.0)

40 (95.2)

0.09

Proton pump inhibitor

572 (94.9)

120 (90.9)

34 (81.0)

0.002

Beta-blocker

565 (93.7)

121 (91.7)

40 (95.2)

0.7

Nitrate

66 (10.9)

20 (15.2)

8 (19.0)

0.1

  1. Data are expressed as means ± SD, medians (first to third quartiles) or n (%). CABG = coronary artery bypass grafting; NSTEMI = non ST segment elevation myocardial infarction; PCI = percutaneous coronary intervention; STEMI = ST segment elevation myocardial infarction; TIA = transient ischemic attack
  2. *No patient was on oral anticoagulant treatment