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Table 1 Demographic and clinical characteristics of patients by diabetic status and type of treatment

From: Diabetes mellitus and platelet reactivity in patients under prasugrel or ticagrelor treatment: an observational study

  No diabetes mellitus Diabetes mellitus non insulin-treated Diabetes mellitus insulin-treated p-value
N = 603 N = 132 N = 42
Male gender 519 (86.1) 116 (87.9) 38 (90.5) 0.7
Age (years) 58.9 ± 11.2 63.4 ± 10.4 62.8 ± 10.5 <0.001
Body mass index (Kg/m2) 28.1 ± 4.2 29.2 ± 4.5 29.2 ± 5.7 0.01
Dyslipidemia 300 (49.8) 72 (54.5) 19 (45.2) 0.5
Hypertension 286 (47.4) 94 (71.2) 21 (50.0) <0.001
Current smoking 39 (6.5) 4 (3.0) 2 (4.8) 0.3
Prior myocardial infarction 45 (7.5) 10 (7.6) 4 (9.5) 0.8
Prior CABG 9 (1.5) 2 (1.5) 2 (4.8) 0.3
Prior PCI 58 (9.6) 12 (9.1) 4 (9.5) 1.0
Prior stroke/TIA 10 (1.7) 6 (4.5) 1 (2.4) 0.2
Admission for PCI   0.2
STEMI 342 (56.7) 63 (47.7) 26 (61.9)  
NSTEMI 161 (26.7) 40 (30.3) 7 (16.7)  
Unstable angina 100 (16.6) 29 (22.0) 9 (21.4)  
Creatinine clearance <60 ml/min 51 (8.5) 18 (13.6) 11 (26.2) 0.001
P2Y12 receptor blocker at discharge and follow-up 0.7
Ticagrelor 363 (60.2) 76 (57.6) 23 (54.8)  
Prasugrel 240 (39.8) 56 (42.4) 19 (45.2)  
Other discharge medication*
Aspirin 100 mg 598 (99.2) 131 (99.2) 42 (100) 1.0
Statin 595 (98.7) 128 (97.0) 40 (95.2) 0.09
Proton pump inhibitor 572 (94.9) 120 (90.9) 34 (81.0) 0.002
Beta-blocker 565 (93.7) 121 (91.7) 40 (95.2) 0.7
Nitrate 66 (10.9) 20 (15.2) 8 (19.0) 0.1
  1. Data are expressed as means ± SD, medians (first to third quartiles) or n (%). CABG = coronary artery bypass grafting; NSTEMI = non ST segment elevation myocardial infarction; PCI = percutaneous coronary intervention; STEMI = ST segment elevation myocardial infarction; TIA = transient ischemic attack
  2. *No patient was on oral anticoagulant treatment