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Table 1 Aortic endothelial responses of KO and WT mice after 8 weeks of HFD vs. chow

From: Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes

Genbank accession Gene name WT H/C KO H/C
NM_007606 carbonic anhydrase 3 −3.66 −3.81
NM_007617 caveolin 3 1.49 2.91
NM_007728 coagulation factor C homolog −1.42 −2.07
NM_007736 collagen, type IV, alpha 5 0.68 2.17
NM_007925 Elastin 1.06 1.79
NM_007940 epoxide hydrolase 2, cytoplasmic −0.84 −1.42
NM_008764 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) 1.32 4.04
NM_008966 prostaglandin F receptor 0.98 2.01
NM_009204 solute carrier 2a4 (Glut4) −1.06 −2.19
NM_009325 thromboxane A2 receptor 1.19 1.43
NM_009605 adiponectin, C1Q and collagen domain containing −5.47 −4.11
NM_009928 collagen, type XV, alpha 1 1.95 2.96
NM_010171 coagulation factor III 0.83 1.58
NM_010570 insulin receptor substrate 1 0.51 1.34
NM_010766 macrophage receptor with collagenous structure 1.07 4.14
NM_011101 protein kinase C, alpha 0.75 2.39
NM_011580 thrombospondin 1 −1.71 −0.20
NM_013459 complement factor D (adipsin) −4.26 −4.02
NM_018762 glycoprotein 9 (platelet) −0.50 −2.77
NM_020509 resistin like alpha −4.44 −2.45
NM_021282 cytochrome P450, family 2, subfamily e, polypeptide 1 −4.50 −4.79
NM_022984 Resistin −4.27 −4.49
NM_026280 matrix-remodelling associated 7 1.27 1.94
NM_028784 coagulation factor XIII, A1 subunit −2.32 −0.97
NM_053185 collagen, type IV, alpha 6 0.76 1.75
NM_153526 insulin induced gene 1 −0.30 −1.34
NM_178793 collagen and calcium binding EGF domains 1 0.07 1.48
  1. Transcripts shown are dysregulated > 1log2 [fold change] in either KO or WT compared to their respective chow-fed controls