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Fig. 9 | Cardiovascular Diabetology

Fig. 9

From: Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance

Fig. 9

2-D Echocardiography of wild type (iNOS+/+) and knockout (iNOS−/−) mice before (Basal) and 5 h after intraperitoneal lipopolysaccharide (2 mg/kg LPS, IP) (Group 2B). Heart rate (in beats/min) (a), stroke volume (in μL) (b), cardiac output (in ml/min) (c), fractional shortening (%) (d), and ejection fraction (%) (e) were determined using M-mode echocardiographic measurements. Data are expressed as mean ± SEM (n = 7–8). * p < 0.05 vs. basal; or wild-type (iNOS+/+) vs. knock-out (KO; iNOS−/−) via two-way ANOVA

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