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Table 1 Baseline biochemical and clinical characteristics of male and female populations. All values are means, medians and mean absolute deviation (MAD)

From: Sex influenced association of directly measured insulin sensitivity and serum transaminase levels: Why alanine aminotransferase only predicts cardiovascular risk in men?

  NGT males (n = 74) GI males (n = 74)
  Mean ± SD Median MAD Mean ± SD Median MAD
Age (years) 33.43 ± 11.60 30.00 10.46 48.72 ± 9.33** 51.40 7.75
BMI (kg/m2) 26.66 ± 5.01 25.10 2.42 29.99 ± 4.30** 29.41 4.01
AC (cm) 94.54 ± 13.11 90.50 6.67 105.07 ± 14.55** 105.00 9.64
HbA1C (%) 5.41 ± 0.43 5.40 0.44 5.90 ± 0.68** 5.80 0.59
Glu-0 (mmol/L) 4.89 ± 0.72 4.83 0.56 6.09 ± 1.04** 5.96 0.96
M3 (mg/min/kg) 8.83 ± 3.10 8.81 2.82 5.88 ± 2.77** 5.74 2.38
HIRI 54.42 ± 33.06 48.86 24.98 63.86 ± 33.84** 60.24 32.09
TG (mmol/l) 1.46 ± 1.14 1.07 0.55 2.65 ± 2.18** 2.00 1.33
HDL-C (mmol/L) 1.35 ± 0.40 1.36 0.36 1.13 ± 0.42** 1.08 0.29
LDL-C (mmol/L) 2.48 ± 0.83 2.31 0.80 3.00 ± 1.05** 3.03 0.79
AST (U/L) 21.68 ± 5.44 20.00 4.45 27.57 ± 12.93** 25.00 8.90
ALT (U/L) 24.81 ± 10.56 22.00 7.41 36.24 ± 26.98** 29.50 15.57
GGT (U/L) 26.93 ± 15.73 22.00 10.38 48.44 ± 33.50** 39.00 28.17
Alcohol (g/day) 0.09 ± 0.38 0.00 0.00 0.30 ± 0.67** 0.00 0.00
Hypertension (%) 10.81 NA NA 43.24 NA NA
Smoking (%) 14.86 NA NA 20.22 NA NA
Genetic predisposition (%) 21.62 NA NA 32.89 NA NA
  NGT females (n = 47) GI females (n = 111)
Age (years) 45.10 ± 10.39 46.00 10.43 50.80 ± 8.54** 53.00 7.41
BMI (kg/m2) 26.85 ± 4.25 26.57 4.74 31.49 ± 5.25** 31.57 4.96
AC (cm) 91.95 ± 12.18 92.00 14.08 104.42 ± 12.49** 103.00 11.86
HbA1C (%) 5.62 ± 0.50 5.60 0.59 6.06 ± 0.63** 6.02 0.62
Glu-0 (mmol/L) 5.08 ± 0.49 5.08 0.44 5.75 ± 0.77** 5.65 0.76
M3 (mg/min/kg) 6.64 ± 3.24 6.29 2.79 4.36 ± 2.08** 3.92 1.69
HIRI 63.07 ± 32.51 54.76 27.80 75.23 ± 49.42** 60.77 36.46
TG (mmol/l) 1.43 ± 0.83 1.24 0.43 1.79 ± 0.81** 1.57 0.74
HDL-C (mmol/L) 1.48 ± 0.55 1.49 0.61 1.33 ± 0.51 1.27 0.36
LDL-C (mmol/L) 2.65 ± 0.81 2.51 0.61 3.20 ± 1.06** 3.17 0.87
AST (U/L) 23.00 ± 9.76 21.00 5.93 23.75 ± 10.37 20.00 4.45
ALT (U/L) 21.79 ± 14.21 20.00 10.38 25.33 ± 12.98* 22.00 8.90
GGT (U/L) 25.95 ± 28.13 19.00 11.86 31.76 ± 25.29** 25.00 11.86
Alcohol (g/day) 0.14 ± 0.55 0.00 0.00 0.02 ± 0.15 0.00 0.00
Hypertension (%) 23.40 NA NA 43.24 NA NA
Smoking (%) 14.86 NA NA 18.18 NA NA
Genetic predisposition (%) 21.62 NA NA 36.36. NA NA
  1. Significant differences between groups are indicated (Wilcoxon rank sum test, *: p < 0.05, **: <0.01). The prevalence of genetic predisposition to T2DM, hypertension is indicated in percentage
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Cardiovascular Diabetology

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